CLOCK 抗体
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北京 101111
Quick Overview for CLOCK 抗体 (ABIN272135)
抗原
See all CLOCK 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Clock protein. (region surrounding Glu270)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-Clock Homolog (Mouse) (CLOCK) (AA 75-109), (N-Term) antibody
CLOCK 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Clock Homolog (Mouse) (CLOCK) (Internal Region) antibodyCLOCK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Clock Homolog (Mouse) (CLOCK) (AA 577-846) antibodyCLOCK 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Clock Homolog (Mouse) (CLOCK) antibodyCLOCK 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 8F7 unconjugated
anti-Clock Homolog (Mouse) (CLOCK) (AA 577-846) antibodyCLOCK 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Clock Homolog (Mouse) (CLOCK) (AA 497-596) antibodyCLOCK 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Clock Homolog (Mouse) (CLOCK) (C-Term) antibodyCLOCK 适用: 人, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Clock Homolog (Mouse) (CLOCK) antibodyCLOCK 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 8F7 unconjugated
anti-Clock Homolog (Mouse) (CLOCK) antibodyCLOCK 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB3455 unconjugated Recombinant Antibody
anti-Clock Homolog (Mouse) (CLOCK) (AA 796-846) antibodyCLOCK 适用: 人, 小鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CLOCK (Clock Homolog (Mouse) (CLOCK))
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别名
- CLOCK
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背景
- Biological timepieces called circadian clocks are responsible for the regulation of hormonal rhythms, sleep cycles and other behaviors. The superchiasmatic nucleus (SCN), which is located in the brain, was the first mammalian circadian clock to be discovered. Clock, a member of the basic-helix-loop-helix-PAS (bHLH-PAS) family of transcription factors, has also been identified as having circadian function. Mutations within the Clock gene have been shown to increase the length of the endogenous period and to cause a loss of rhythmicity of circadian oscillations. Clock contains a DNA-binding domain, a protein dimerization domain and a glutamine-rich C-terminal region, which indicates transactivation capabilities. It has been speculated that Clock may regulate circadian rhythmicity in combination with other proteins such as Per. Per is also a PAS-domain containing protein that exhibits circadian function. Highest expression of Clock is seen in the hypothalamus and the eye.Synonyms: BHLHE8, Circadian locomoter output cycles protein kaput, Class E basic helix-loop-helix protein 8, KIAA0334
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分子量
- approx. 95 kDa
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基因ID
- 9575
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NCBI登录号
- NP_004889
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UniProt
- O15516
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途径
- Regulation of Lipid Metabolism by PPARalpha, Photoperiodism
抗原
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