Tyrosine Hydroxylase 抗体
Our Local Distributor
北京 101111
Quick Overview for Tyrosine Hydroxylase 抗体 (ABIN272085)
抗原
See all Tyrosine Hydroxylase (TH) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- This antibody detects endogenous levels of TH protein. (region surrounding Pro2)
-
交叉反应 （详细）
- Species reactivity (tested):Mouse and Rat.
-
纯化方法
- Affinity Chromatography using epitope-specific immunogen.
-
-
anti-Tyrosine Hydroxylase (TH) (AA 101-165) antibody
TH 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (AA 82-310) antibodyTH 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (pSer40) antibodyTH 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (pSer31) antibodyTH 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) antibodyTH 适用: 人 WB, IF, ICC, IHC (p), IHC (fro), IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (AA 486-514) antibodyTH 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (AA 34-301) antibodyTH 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (pSer19) antibodyTH 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (AA 193-222), (Middle Region) antibodyTH 适用: 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (C-Term) antibodyVerified TH 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
-
-
应用备注
-
ELISA: 1/20000approx. 1/40000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1,0 mg/mL
-
缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- Tyrosine Hydroxylase (TH)
-
别名
- Tyrosine 3-Monooxygenase (TH)
-
背景
- The enzyme tyrosine hydroxylase (TH), also designated tyrosine 3-monooxygenase (TY3H), catalyzes the conversion of tyrosine to L-dopa, which is the rate limiting step in the biosynthesis of catecholamines such as dopamine, adrenalin and noradrenalin. TH is thought to play a role in the pathogenesis of Parkinson's disease, which is associated with reduced dopamine levels. Two transcription factor binding sites in the proximal region of the TH gene, the TPA-responsive element (TRE) and the c-AMP responsive element (CRE), have been implicated in the complex regulation of the TH gene. TH is also known to be upregulated by the glia maturation factor (GMF), a Cdc 10/SWI6 motif-containing protein called V-1, and a variety of additional compounds.Synonyms: TYH, Tyrosine 3-hydroxylase
-
分子量
- approx. 58 kDa
-
基因ID
- 25085
-
NCBI登录号
- NP_036872
-
UniProt
- P04177
-
途径
- Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour
抗原
-
