SOX9 抗体
Our Local Distributor
北京 101111
Quick Overview for SOX9 抗体 (ABIN272082)
抗原
See all SOX9 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- This antibody detects endogenous levels of SOX-9 protein. (region surrounding Gln175).
-
交叉反应 (详细)
- Species reactivity (tested):Human and Mouse.
-
纯化方法
- Affinity Chromatography using epitope-specific immunogen
-
-
-
-
应用备注
-
ELISA: 1/5000approx. 1/10000Western Blot: 1/500approx. 1/1000Immunohistochemistry (Paraffin): 1/50approx. 1/200Immunofluorescence: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
-
: "Differences in the developmental origins of the periosteum may influence bone healing." in: Journal of periodontal research, Vol. 50, Issue 4, pp. 468-78, (2016) (PubMed).
: "Association of hsa-miR‑145 overexpression in human testicular cells with male infertility." in: Molecular medicine reports, Vol. 11, Issue 6, pp. 4365-72, (2015) (PubMed).
: "Proteomic analysis of differentially expressed proteins in vitamin C-treated AGS cells." in: BMC biochemistry, Vol. 14, pp. 24, (2014) (PubMed).
-
-
- SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))
-
别名
- SOX9
-
背景
- Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.Synonyms: CMD1, CMPD1, SRA1, SRY (sex determining region Y)-box 9, SRY-box 9, Transcription factor SOX-9
-
分子量
- approx. 56 kDa
-
基因ID
- 6662
-
NCBI登录号
- NP_000337
-
UniProt
- P48436
-
途径
- EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
抗原
-