PKD2 抗体
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北京 101111
Quick Overview for PKD2 抗体 (ABIN272069)
抗原
See all PKD2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of PKD2 protein. (region surrounding Ala872)
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交叉反应 (详细)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen
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应用备注
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ELISA: 1/5000approx. 1/10000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PKD2 (Protein Kinase D2 (PKD2))
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别名
- PRKD2 / PKD2
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背景
- The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms.Synonyms: HSPC187, PKC-D2, Serine/threonine-protein kinase D2, nPKC-D2
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分子量
- approx. 96 kDa
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基因ID
- 25865
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NCBI登录号
- NP_001073349
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UniProt
- Q9BZL6
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途径
- cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
抗原
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