MST1 抗体
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Quick Overview for MST1 抗体 (ABIN272039)
抗原
See all MST1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of MST1/2 protein. (region surrounding Meth178)
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交叉反应 (详细)
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Species reactivity (tested):Human and Mouse.
Also reacts to: MST2 -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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应用备注
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ELISA: 1: 5000approx. 1: 10000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- MST1 (Macrophage Stimulating 1 (Hepatocyte Growth Factor-Like) (MST1))
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别名
- Macrophage Stimulatory Protein
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背景
- Sterile-20 (STE20) is a serine/threonine kinase in Saccharomyces cerevisiae that is involved in relaying signals from G protein coupled receptors to cytosolic MAP kinase cascades. Mammalian protein kinases that display sequence similarity to STE20 are divided into two groups, the PAK subfamily and the GCK subfamily. The PAK subfamily members contain a C-terminal catalytic domain and an N-terminal regulatory domain with a p21Rac/Cdc42-binding site, and these kinases can activate both p38MAPK and JNK. The GCK subfamily members contain a C-terminal regulatory domain and an Nterminal catalytic domain, and they have diverse roles in many pathways, including the activation of ERK< JNK, p38 MAPK, and caspase-3. The mammalian STE20-like kinases (MST kinases, also known as Ksr proteins) are members of the GCK subfamily.Synonyms: D3F15S2, DNF15S2, HGFL, Hepatocyte growth factor-like protein, Hepatocyte growth factor-like protein alpha chain, Hepatocyte growth factor-like protein beta chain, MSP, MST1, Macrophage-stimulating protein
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分子量
- approx. 65 kDa
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基因ID
- 4485
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NCBI登录号
- NP_066278
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UniProt
- P26927
抗原
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