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EIF4E 抗体

EIF4E 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 6C11 unconjugated
产品编号 ABIN2720090
发货至: 中国
  • 抗原 See all EIF4E 抗体
    EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
    适用
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    宿主
    • 106
    • 15
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    小鼠
    克隆类型
    • 99
    • 24
    单克隆
    标记
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    This EIF4E antibody is un-conjugated
    应用范围
    • 96
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    • 16
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    Western Blotting (WB), Flow Cytometry (FACS)
    产品特性
    Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), transcript variant 1
    纯化方法
    Purified from mouse ascites fluids by affinity chromatography
    免疫原
    Full length human recombinant protein of human EIF4E (NP_001959) produced in HEK293T cell.
    克隆位点
    6C11
    亚型
    IgG1
    Top Product
    Discover our top product EIF4E Primary Antibody
  • 应用备注
    WB 1:500~2000, FLOW 1:100
    说明

    The concentration of the product may vary between diferrent lots.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5-1.0 mg/mL
    缓冲液
    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
    别名
    EIF4E (EIF4E 产品)
    背景
    All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide). This structure is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export. EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F. The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis. The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A (see MIM 601102), that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G (MIM 600495) (Rychlik et al., 1987 [PubMed 3469651]).
    分子量
    24.9 kDa
    基因ID
    1977
    NCBI登录号
    NM_001968
    HGNC
    1977
    途径
    BCR Signaling
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