CEBPE 抗体
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北京 101111
Quick Overview for CEBPE 抗体 (ABIN272001)
抗原
See all CEBPE 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of C/EBP-ε protein. (region surrounding Lys70)
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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应用备注
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ELISA: 1: 1000approx. 1: 5000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IF: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- CEBPE (CCAAT/enhancer Binding Protein (C/EBP), epsilon (CEBPE))
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别名
- CEBPE
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背景
- EBP1 (ErbB-3-binding protein 1), also known as PA2G4 (proliferation-associated 2G4), p38-2G4 or HG4-1, is a member of the peptidase M24C family and functions as an RNA-binding protein involved in cellular proliferation and differentiation processes. It is expressed in a variety of cell lines, including a wide range of tumor cell lines, and localizes to the cytoplasm. Upon treatment with Neuregulin-1 (heregulin), EBP1 translocates to the nucleus. EBP1 is a component of pre-ribosomal ribonucleoprotein complexes, participating in ribosome assembly and regulating the later steps of rRNA processing. In addition, EBP1 interacts with ErbB-3 and may function as a modulator of the ErbB-3-mediated signal transduction pathway by regulating the effects of Neuregulin-1. EBP1 also associates with histone deacetylases (HDACs), functioning as a transcriptional corepressor of cell cycle regulatory genes.Synonyms: C/EBP epsilon, CCAAT/enhancer-binding protein epsilon
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分子量
- approx. 30 kDa
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基因ID
- 1053
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NCBI登录号
- NP_001796
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UniProt
- Q15744
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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