Ubiquitin 抗体
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Quick Overview for Ubiquitin 抗体 (ABIN271973)
抗原
See all Ubiquitin (Ub) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Ubiquitin protein.
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纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-Ubiquitin (Ub) antibody
Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin (Ub) (AA 1-229) antibodyUb 适用: 人, 大鼠, 小鼠, Cow, Pig, 犬, 马, 兔 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin (Ub) (AA 1-229) antibodyUb 适用: 人, 大鼠 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal D2 unconjugated
anti-Ubiquitin (Ub) (acLys27) antibodyUb 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin (Ub) antibody (Atto 390)Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal Atto 390
anti-Ubiquitin (Ub) antibody (Atto 488)Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal Atto 488
anti-Ubiquitin (Ub) antibody (Atto 594)Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal Atto 594
anti-Ubiquitin (Ub) antibody (APC)Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal APC
anti-Ubiquitin (Ub) antibody (Biotin)Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal Biotin
anti-Ubiquitin (Ub) antibody (FITC)Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal FITC
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应用备注
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ELISA: 1/20000approx. 1/40000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "Electrical field stimulation induces cardiac fibroblast proliferation through the calcineurin-NFAT pathway." in: Canadian journal of physiology and pharmacology, Vol. 90, Issue 12, pp. 1611-22, (2012) (PubMed).
: "Gambogic acid-induced degradation of mutant p53 is mediated by proteasome and related to CHIP." in: Journal of cellular biochemistry, Vol. 112, Issue 2, pp. 509-19, (2011) (PubMed).
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- Ubiquitin (Ub)
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别名
- Ubiquitin
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背景
- Ubiquitin is a conserved polypeptide unit that plays an important role in the ubiquitin-proteasome pathway. Ubiquitin can be covalently linked to many cellular proteins by the ubiquitination process, which targets proteins for degradation by the 26S proteasome. Three components are involved in the target protein-ubiquitin conjugation process. Ubiquitin is first activated by forming a thiolester complex with the activation component E1, the activated ubiquitin is subsequently transfered to the ubiquitin-carrier protein E2, then from E2 to ubiquitin ligase E3 for final delivery to the epsilon-NH2 of the target protein lysine residue. The ubiquitin-proteasome pathway has been implicated in a wide range of normal biological processes and in disease-related abnormalities. Several proteins such as IkappaB, p53, cdc25a and Bcl-2 have been shown to be targets for the ubiquitination-proteosome process as part of regulation of cell cycle progression, differentiation, cell stress response and apoptosis.Synonyms: Polyubiquitin-B, UBB
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基因ID
- 7314
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UniProt
- P0CG47
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途径
- Mitotic G1-G1/S Phases, Ubiquitin Proteasome Pathway
抗原
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