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SENP6 抗体

The 兔 多克隆 anti-SENP6 antibody (ABIN271959) specifically detects SENP6 in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN271959
发货至: 中国
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Quick Overview for SENP6 抗体 (ABIN271959)

抗原

See all SENP6 抗体
SENP6 (SUMO1/sentrin Specific Protease 6 (SENP6))

适用

  • 50
  • 6
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 44
  • 5
  • 1

克隆类型

  • 45
  • 5
多克隆

标记

  • 22
  • 6
  • 4
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SENP6 antibody is un-conjugated

应用范围

  • 32
  • 27
  • 22
  • 12
  • 5
  • 4
  • 3
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of SENP6 protein. (region surrounding Lys1077)

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography using epitope-specific immunogen.
  • 应用备注

    ELISA: 1/10000approx. 1/20000. Immunohistochemistry: 1/50approx. 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    SENP6 (SUMO1/sentrin Specific Protease 6 (SENP6))

    别名

    SENP6

    背景

    Covalent attachment of one protein to another is one of the more prominent posttranslational modifications in respects to size and ubiquity - to which eukaryotic proteins are subject. Ubiquitin is the most familiar of the protein modifiers and its activation and transfer to target proteins has been studied for over two decades. Recently a new group of ubiquitin-like (Ubl) proteins have come to light. One of the most intriguing of them is SUMO (small ubiquitin-like modifier, ~12 kDa) also known as Sentrin. SUMO family has been described in vertebrates: SUMO-1 and the closest homologs SUMO-2 and SUMO-3. SUMO have been shown to bind and regulate mammalian SP-RINGs (such as Mdm2, PIAS and PML), RanGAP1, RanBP2, p53, p73, HIPK2, TEL, c-Jun, Fas, Daxx, TNFRI, Topo-I, Topo-II, WRN, Sp100, IkB-alpha, Androgen receptor (AR), GLUT1/4, Drosophila Ttk69, Dorsal, CaMK, yeast Septins, and viral CMV-IE1/2, EBV-BZLF1, HPV/BPV-E1. These bindings implicate SUMO in the stabilization of the target proteins and/or their localization to subcellular complexes. SUMO research enters now an exciting phase with a promise to help understanding how cells orchestrate the complexities of rapidly regulating protein level and activity.Synonyms: KIAA0797, SSP1, SUMO-1-specific protease 1, SUSP1, Sentrin-specific protease 6, Sentrin/SUMO-specific protease SENP6

    基因ID

    26054

    NCBI登录号

    NP_001093879

    UniProt

    Q9GZR1
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