NUB1 抗体
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北京 101111
Quick Overview for NUB1 抗体 (ABIN271950)
抗原
See all NUB1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of NUB1 protein. (region surrounding Tyr601)
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交叉反应 (详细)
- Species reactivity (tested):Human, Mouse.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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应用备注
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ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- NUB1 (Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1))
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别名
- NUB1
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背景
- NUB1 is a ubiquitin-like protein that controls vital biological events through its conjugation to cullin proteins. NUB1 is a negative regulator of the NEDD8 system that recruits NEDD8 and its conjugates to the proteasome for degradation. It is, therefore a cell growth regulator. The UBA domain of NUB1 is the specific acceptor for the linear ubiquitin precursor. NUB1 is composed of 601 amino acids. It is an interferon-inducible protein and predominantly localizes in the nucleus. NUB1 is specifically expressed in adult human testis, ovary, heart, and skeletal muscle tissues.Synonyms: NEDD8 μLtimate buster 1, NYREN18, Negative regulator of ubiquitin-like proteins 1, Renal carcinoma antigen NY-REN-18
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分子量
- approx. 70 kDa
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基因ID
- 51667
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NCBI登录号
- NP_057202
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UniProt
- Q9Y5A7
抗原
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