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NUB1 抗体

NUB1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN271950
发货至: 中国
  • 抗原 See all NUB1 抗体
    NUB1 (Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1))
    适用
    • 35
    • 13
    • 3
    • 2
    • 1
    人, 小鼠
    宿主
    • 31
    • 3
    • 1
    克隆类型
    • 33
    • 2
    多克隆
    标记
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NUB1 antibody is un-conjugated
    应用范围
    • 28
    • 20
    • 18
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of NUB1 protein. (region surrounding Tyr601)
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product NUB1 Primary Antibody
  • 应用备注
    ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    DO NOT FREEZE!
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    NUB1 (Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1))
    别名
    NUB1 (NUB1 产品)
    背景
    NUB1 is a ubiquitin-like protein that controls vital biological events through its conjugation to cullin proteins. NUB1 is a negative regulator of the NEDD8 system that recruits NEDD8 and its conjugates to the proteasome for degradation. It is, therefore a cell growth regulator. The UBA domain of NUB1 is the specific acceptor for the linear ubiquitin precursor. NUB1 is composed of 601 amino acids. It is an interferon-inducible protein and predominantly localizes in the nucleus. NUB1 is specifically expressed in adult human testis, ovary, heart, and skeletal muscle tissues.Synonyms: NEDD8 μLtimate buster 1, NYREN18, Negative regulator of ubiquitin-like proteins 1, Renal carcinoma antigen NY-REN-18
    分子量
    approx. 70 kDa
    基因ID
    51667
    NCBI登录号
    NP_057202
    UniProt
    Q9Y5A7
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