PLA2G4B 抗体
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- 抗原 See all PLA2G4B 抗体
- PLA2G4B (Phospholipase A2, Group IVB (Cytosolic) (PLA2G4B))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PLA2G4B antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of c-PLA2 protein. (region surrounding asn499)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product PLA2G4B Primary Antibody
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anti-Phospholipase A2, Group IVB (Cytosolic) (PLA2G4B) (AA 514-781) antibody
PLA2G4B 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase A2, Group IVB (Cytosolic) (PLA2G4B) antibodyPLA2G4B 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase A2, Group IVB (Cytosolic) (PLA2G4B) (C-Term) antibodyPLA2G4B 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase A2, Group IVB (Cytosolic) (PLA2G4B) (N-Term) antibodyPLA2G4B 适用: 人, 小鼠, 大鼠, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase A2, Group IVB (Cytosolic) (PLA2G4B) (AA 396-424) antibodyPLA2G4B 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB21321 unconjugated
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- 应用备注
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ELISA: (1/10000approx. 1/20000). Western Blot (1/500approx. 1/1000). Immunohistochemistry (1/50approx. 1/200). Immunofluorescence (1/50approx. 1/200)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- PLA2G4B (Phospholipase A2, Group IVB (Cytosolic) (PLA2G4B))
- 别名
- PLA2G4B (PLA2G4B 产品)
- 别名
- HsT16992 antibody, cPLA2-beta antibody, A030011C02Rik antibody, Gm1013 antibody, phospholipase A2 group IVB antibody, phospholipase A2, group IVB (cytosolic) antibody, PLA2G4B antibody, Pla2g4b antibody
- 背景
- Phospholipase A2s (PLA2s) constitute a family of esterases that hydrolyze the sn-2-acyl ester bond in glycerophospholipid molecules. These enzymes are generally calcium-dependent and have been found both intra- and extracellularly. By hydrolyzing the sn-2 bond in glycerophospholipids, PLA2s release fatty acids. One such fatty acid, arachidonic acid, generates the substrates for the initiation of the arachidonic acid cascade that produces various eicosanoids (i.e. prostaglandins, leukotrienes and thromboxanes), many of which are potent mediators of inflammation. PLA2s include both the relatively low molecular weight type I and type II enzymes and the form known as cytoplasmic PLA2 (cPLA2). cPLA2 is present in the cytosol of various cells and tissues including platelets, macrophages and monoblasts, and preferentially hydrolyzes the sn-2 position of phospholipid molecules, releasing free arachidonate.Synonyms: Cytosolic phospholipase A2 beta, Phospholipase A2 group IVB, cPLA2-beta, phospholipase A2 beta
- 分子量
- approx. 100 kDa
- 基因ID
- 100137049
- NCBI登录号
- NP_001108105
- UniProt
- P0C869
- 途径
- ER-Nucleus Signaling, VEGF Signaling
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