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Dynamin 1 抗体

This anti-Dynamin 1 antibody is a 兔 多克隆 antibody detecting Dynamin 1 in WB, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN271884
发货至: 中国

Quick Overview for Dynamin 1 抗体 (ABIN271884)

抗原

See all Dynamin 1 (DNM1) 抗体
Dynamin 1 (DNM1)

适用

  • 102
  • 44
  • 42
  • 10
  • 9
  • 8
  • 3
  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 93
  • 11
  • 3

克隆类型

  • 103
  • 5
多克隆

标记

  • 53
  • 5
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Dynamin 1 antibody is un-conjugated

应用范围

  • 91
  • 39
  • 39
  • 36
  • 24
  • 13
  • 13
  • 7
  • 7
  • 4
  • 3
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody detects endogenous levels of Dynamin-1 protein. (region surrounding Val768)

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography using epitope-specific immunogen.
  • 应用备注

    ELISA: 1:5000approx. 1:10000. WB: 1:500approx. 1:1000. IHC: 1:50approx. 1:200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Dynamin 1 (DNM1)

    别名

    Dynamin-1

    背景

    Members of the Dynamin family, including Dynamin I and Dynamin II, are GTPase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin I is localized to the central nervous system, while Dynamin II exhibits ubiquitous distribution with highest expression in testis. Both Dynamin proteins contain SH3 and proline-rich domains that mediate interactions between the Dynamins and effectors of their GTPase activity. The interactions with these effectors, which include microtubules, acidic phospholipids and SH3 domain-containing proteins, are required for rapid endocytosis. Dynamin I appears to be recruited to Clathrin coated pits by SH3 domain interaction with Amphiphysin, a protein highly expressed in brain.Synonyms: DNM, DNM1

    分子量

    approx. 98 kDa

    基因ID

    1759

    NCBI登录号

    NP_001005336

    UniProt

    Q05193

    途径

    Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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