Acetyl-CoA Carboxylase alpha 抗体
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- 抗原 See all Acetyl-CoA Carboxylase alpha (ACACA) 抗体
- Acetyl-CoA Carboxylase alpha (ACACA)
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Acetyl-CoA Carboxylase alpha antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of Acetyl-CoA Carboxylase protein. (region surrounding His74)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product ACACA Primary Antibody
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anti-Acetyl-CoA Carboxylase alpha (ACACA) antibody
ACACA 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) antibodyACACA 适用: 人, 大鼠, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) (N-Term) antibodyACACA 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) (pSer79) antibodyACACA 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) antibodyACACA 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) (Ser122) antibodyACACA 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) (pSer80) antibodyACACA 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) (AA 1-99) antibodyACACA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6H5 unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) (Ser80) antibodyACACA 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) (Ser79) antibodyACACA 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/5000-1/10000. Western blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Acetyl-CoA Carboxylase alpha (ACACA)
- 别名
- Acetyl-CoA Carboxylase 1 (ACACA 产品)
- 别名
- ACAC antibody, ACACAD antibody, ACC antibody, ACC1 antibody, ACCA antibody, A530025K05Rik antibody, Acac antibody, Acc1 antibody, Gm738 antibody, AT-ACC1 antibody, EMB22 antibody, EMBRYO DEFECTIVE 22 antibody, GK antibody, GURKE antibody, PAS3 antibody, PASTICCINO 3 antibody, acetyl-CoA carboxylase 1 antibody, acc antibody, fj43d01 antibody, im:7138837 antibody, si:ch211-199d18.1 antibody, wu:fj43d01 antibody, acetyl-CoA carboxylase alpha antibody, acetyl-Coenzyme A carboxylase alpha antibody, acetyl-CoA carboxylase 1 antibody, ACACA antibody, Acaca antibody, ACC1 antibody, acaca antibody
- 背景
- Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the ratelimiting step in fatty acid synthesis. Exercise diminishes the activity of acetyl-CoA carboxylase in human muscle. ACC-alpha (ACC1) is the rate-limiting enzyme in the biogenesis of long-chain fatty acids, and ACC-beta (ACC2) may control mitochondrial fatty acid oxidation. These two isoforms of ACC control the amount of fatty acids in the cells. The catalytic function of ACC-alpha is regulated by phosphorylation (inactive) and dephosphorylation (active) of targeted Serine residues and by allosteric transformation by citrate or palmitoyl-CoA, which serve as the short-term regulatory mechanism of the enzyme. The gene encoding ACC-alpha, which maps to human chromosome 17, encodes the 265 kDa alpha form of ACC, which is the major ACC in lipogenic tissues. The catalytic core of ACC-beta is homologous to that of ACC-alpha except for an additional peptide of about 150 amino acids at the N-terminus.Synonyms: ACAC, ACACA, ACC1, ACCA
- 分子量
- approx. 265 kDa
- 基因ID
- 31
- NCBI登录号
- NP_942131
- UniProt
- Q13085
- 途径
- AMPK Signaling, Ribonucleoside Biosynthetic Process, Warburg Effect
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