Acetyl-CoA Carboxylase alpha 抗体
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- 抗原 See all Acetyl-CoA Carboxylase alpha (ACACA) 抗体
- Acetyl-CoA Carboxylase alpha (ACACA)
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Acetyl-CoA Carboxylase alpha antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of ACC1 protein.
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product ACACA Primary Antibody
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anti-Acetyl-CoA Carboxylase alpha (ACACA) antibody
ACACA 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) antibodyACACA 适用: 人, 大鼠, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) (N-Term) antibodyACACA 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) (pSer79) antibodyACACA 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) antibodyACACA 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) (Ser122) antibodyACACA 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) (pSer80) antibodyACACA 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) (AA 1-99) antibodyACACA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6H5 unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) (Ser80) antibodyACACA 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) (Ser79) antibodyACACA 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/1000-1/5000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS, pH 7.2, 0.05 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Acetyl-CoA Carboxylase alpha (ACACA)
- 别名
- Acetyl-CoA Carboxylase 1 (ACACA 产品)
- 别名
- ACAC antibody, ACACAD antibody, ACC antibody, ACC1 antibody, ACCA antibody, A530025K05Rik antibody, Acac antibody, Acc1 antibody, Gm738 antibody, AT-ACC1 antibody, EMB22 antibody, EMBRYO DEFECTIVE 22 antibody, GK antibody, GURKE antibody, PAS3 antibody, PASTICCINO 3 antibody, acetyl-CoA carboxylase 1 antibody, acc antibody, fj43d01 antibody, im:7138837 antibody, si:ch211-199d18.1 antibody, wu:fj43d01 antibody, acetyl-CoA carboxylase alpha antibody, acetyl-Coenzyme A carboxylase alpha antibody, acetyl-CoA carboxylase 1 antibody, ACACA antibody, Acaca antibody, ACC1 antibody, acaca antibody
- 背景
- Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the ratelimiting step in fatty acid synthesis. Exercise diminishes the activity of acetyl- CoA carboxylase in human muscle. ACCα (ACC1) is the rate-limiting enzyme in the biogenesis of long-chain fatty acids, and ACCβ (ACC2) may control mitochondrial fatty acid oxidation. These two isoforms of ACC control the amount of fatty acids in the cells. The catalytic function of ACCα is regulated by phosphorylation (inactive) and dephosphorylation (active) of targeted Serine residues and by allosteric transformation by citrate or palmitoyl-CoA, which serve as the short-term regulatory mechanism of the enzyme. The gene encoding ACCα, which maps to human chromosome 17, encodes the 265 kDa α form of ACC, which is the major ACC in lipogenic tissues. The catalytic core of ACCβ is homologous to that of ACCα except for an additional peptide of about 150 amino acids at the N-terminus.Synonyms: ACAC, ACACA, ACC1, ACCA
- 分子量
- approx. 265 kDa
- 基因ID
- 31
- NCBI登录号
- NP_942131
- UniProt
- Q13085
- 途径
- AMPK Signaling, Ribonucleoside Biosynthetic Process, Warburg Effect
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