PVRL1 抗体
Quick Overview for PVRL1 抗体 (ABIN2717248)
抗原
See all PVRL1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
产品特性
- Homo sapiens poliovirus receptor-related 1 (herpesvirus entry mediator C) (PVRL1), transcript variant 1
-
纯化方法
- Purified from mouse ascites fluids by affinity chromatography
-
免疫原
- Full length human recombinant protein of human PVRL1(NP_002846) produced in HEK293T cell.
-
亚型
- IgG2a
-
-
-
-
应用备注
- WB 1:2000, IHC 1:150, IF 1:100,
-
说明
-
The concentration of the product may vary between diferrent lots.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5-1.0 mg/mL
-
缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
-
- PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))
-
别名
- PVRL1
-
背景
- This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.
-
分子量
- 54 kDa
-
基因ID
- 5818
-
NCBI登录号
- NM_002855
-
HGNC
- 5818
-
途径
- Cell-Cell Junction Organization
抗原
-