PVRL1 抗体
-
- 抗原 See all PVRL1 抗体
- PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This PVRL1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 产品特性
- Homo sapiens poliovirus receptor-related 1 (herpesvirus entry mediator C) (PVRL1), transcript variant 1
- 纯化方法
- Purified from mouse ascites fluids by affinity chromatography
- 免疫原
- Full length human recombinant protein of human PVRL1(NP_002846) produced in HEK293T cell.
- 克隆位点
- 1B6
- 亚型
- IgG2a
- Top Product
- Discover our top product PVRL1 Primary Antibody
-
-
- 应用备注
- WB 1:2000, IHC 1:150, IF 1:100,
- 说明
-
The concentration of the product may vary between diferrent lots.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.5-1.0 mg/mL
- 缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
-
- 抗原
- PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))
- 别名
- PVRL1 (PVRL1 产品)
- 背景
- This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.
- 分子量
- 54 kDa
- 基因ID
- 5818
- NCBI登录号
- NM_002855
- HGNC
- 5818
- 途径
- Cell-Cell Junction Organization
-