Catalase 抗体
Quick Overview for Catalase 抗体 (ABIN2717106)
抗原
See all Catalase (CAT) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Homo sapiens catalase (CAT)
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纯化方法
- Purified from mouse ascites fluids by affinity chromatography
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免疫原
- Full length human recombinant protein of human CAT (NP_111743) produced in HEK293T cell.
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亚型
- IgG1
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应用备注
- WB 1:200~500, IHC 1:150, IF 1:100,
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说明
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The concentration of the product may vary between diferrent lots.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5-1.0 mg/mL
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缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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: "Pterostilbene Decreases the Antioxidant Defenses of Aggressive Cancer Cells In Vivo: A Physiological Glucocorticoids- and Nrf2-Dependent Mechanism." in: Antioxidants & redox signaling, Vol. 24, Issue 17, pp. 974-90, (2016) (PubMed).
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: "Pterostilbene Decreases the Antioxidant Defenses of Aggressive Cancer Cells In Vivo: A Physiological Glucocorticoids- and Nrf2-Dependent Mechanism." in: Antioxidants & redox signaling, Vol. 24, Issue 17, pp. 974-90, (2016) (PubMed).
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- Catalase (CAT)
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别名
- CAT
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背景
- This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.
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分子量
- 59.6 kDa
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基因ID
- 847
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NCBI登录号
- NM_001752
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HGNC
- 847
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途径
- Cellular Glucan Metabolic Process, Cell RedoxHomeostasis, Photoperiodism
抗原
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