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BCL10 抗体

BCL10 适用: 人 WB, IF, FACS 宿主: 小鼠 Monoclonal 6A4 unconjugated
产品编号 ABIN2716551
发货至: 中国
  • 抗原 See all BCL10 抗体
    BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
    适用
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    小鼠
    克隆类型
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    单克隆
    标记
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    This BCL10 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    产品特性
    Homo sapiens B-cell CLL/lymphoma 10 (BCL10)
    纯化方法
    Purified from mouse ascites fluids by affinity chromatography
    免疫原
    Full length human recombinant protein of human BCL10 (NP_003912) produced in HEK293T cell.
    克隆位点
    6A4
    亚型
    IgG1
    Top Product
    Discover our top product BCL10 Primary Antibody
  • 应用备注
    WB 1:2000, IF 1:100, FLOW 1:100
    说明

    The concentration of the product may vary between diferrent lots.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5-1.0 mg/mL
    缓冲液
    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
    别名
    BCL10 (BCL10 产品)
    别名
    CARMEN antibody, CIPER antibody, CLAP antibody, c-E10 antibody, mE10 antibody, BCL10 antibody, AI132454 antibody, BCL-10 antibody, C81403 antibody, ME10 antibody, cE10 antibody, bcl10 antibody, B-cell CLL/lymphoma 10 antibody, B-cell lymphoma/leukemia 10-like antibody, B cell leukemia/lymphoma 10 antibody, B-cell lymphoma/leukemia 10 antibody, BCL10 antibody, Bcl10 antibody, bcl10 antibody, LOC100223183 antibody
    背景
    This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.
    分子量
    26.1 kDa
    基因ID
    8915
    NCBI登录号
    NM_003921
    HGNC
    8915
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
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