BCAT1 抗体
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北京 101111
Quick Overview for BCAT1 抗体 (ABIN2716546)
抗原
See all BCAT1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Homo sapiens branched chain amino-acid transaminase 1, cytosolic (BCAT1), transcript variant 1
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纯化方法
- Purified from mouse ascites fluids by affinity chromatography
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免疫原
- Full length human recombinant protein of human BCAT1(NP_005495) produced in HEK293T cell.
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亚型
- IgG2a
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应用备注
- WB 1:500~2000, IHC 1:150,
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说明
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The concentration of the product may vary between diferrent lots.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5-1.0 mg/mL
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缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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: "BCAT1 is a New MR Imaging-related Biomarker for Prognosis Prediction in IDH1-wildtype Glioblastoma Patients." in: Scientific reports, Vol. 7, Issue 1, pp. 17740, (2017) (PubMed).
: "Cancer progression by reprogrammed BCAA metabolism in myeloid leukaemia." in: Nature, Vol. 545, Issue 7655, pp. 500-504, (2017) (PubMed).
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- BCAT1 (Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1))
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别名
- BCAT1
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背景
- This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described.
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分子量
- 42.8 kDa
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基因ID
- 586
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NCBI登录号
- NM_005504
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HGNC
- 586
抗原
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