RFXANK 抗体
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- 抗原 See all RFXANK 抗体
- RFXANK (Regulatory Factor X-Associated Ankyrin Containing Protein (RFXANK))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This RFXANK antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS)
- 产品特性
- Homo sapiens regulatory factor X-associated ankyrin-containing protein (RFXANK), transcript variant 2
- 纯化方法
- Purified from mouse ascites fluids by affinity chromatography
- 免疫原
- Full length human recombinant protein of human RFXANK(NP_604389) produced in HEK293T cell.
- 克隆位点
- 3C10
- 亚型
- IgG1
- Top Product
- Discover our top product RFXANK Primary Antibody
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- 应用备注
- WB 1:500, IHC 1:150, IF 1:100, FLOW 1:100,
- 说明
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The concentration of the product may vary between diferrent lots.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5-1.0 mg/mL
- 缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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- 抗原
- RFXANK (Regulatory Factor X-Associated Ankyrin Containing Protein (RFXANK))
- 别名
- RFXANK (RFXANK 产品)
- 背景
- Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Two transcript variants encoding different isoforms have been described for this gene, with only one isoform showing activation activity.
- 分子量
- 25.4 kDa
- 基因ID
- 8625
- NCBI登录号
- NM_134440
- HGNC
- 8625
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