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Aminoacylase 1 抗体

This anti-Aminoacylase 1 antibody is a 小鼠 单克隆 antibody detecting Aminoacylase 1 in WB 和 FACS. Suitable for 人.
产品编号 ABIN2716053
发货至: 中国
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Aminoacylase 1 抗体 (ABIN2716053)

抗原

See all Aminoacylase 1 (ACY1) 抗体
Aminoacylase 1 (ACY1)

适用

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宿主

  • 24
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小鼠

克隆类型

  • 26
  • 14
单克隆

标记

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This Aminoacylase 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

1H9
  • 产品特性

    Homo sapiens aminoacylase 1 (ACY1), transcript variant 1

    纯化方法

    Purified from mouse ascites fluids by affinity chromatography

    免疫原

    Full length human recombinant protein of human ACY1 (NP_000657) produced in HEK293T cell.

    亚型

    IgG1
  • 应用备注

    WB 1:2000, FLOW 1:100,

    说明

    The concentration of the product may vary between diferrent lots.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5-1.0 mg/mL

    缓冲液

    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    Aminoacylase 1 (ACY1)

    别名

    ACY1

    背景

    This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18.

    分子量

    45.7 kDa

    基因ID

    95

    NCBI登录号

    NM_000666

    HGNC

    95
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