Aminoacylase 1 抗体
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- 抗原 See all Aminoacylase 1 (ACY1) 抗体
- Aminoacylase 1 (ACY1)
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适用
- 人, 小鼠, 大鼠, 犬
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Aminoacylase 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
- 产品特性
- Homo sapiens aminoacylase 1 (ACY1), transcript variant 1
- 纯化方法
- Purified from mouse ascites fluids by affinity chromatography
- 免疫原
- Full length human recombinant protein of human ACY1(NP_000657) produced in HEK293 cell.
- 克隆位点
- 2D3
- 亚型
- IgG1
- Top Product
- Discover our top product ACY1 Primary Antibody
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- 应用备注
- WB 1:200~500, IHC 1:150, FLOW 1:100,
- 说明
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The concentration of the product may vary between diferrent lots.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5-1.0 mg/mL
- 缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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- 抗原
- Aminoacylase 1 (ACY1)
- 别名
- ACY1 (ACY1 产品)
- 背景
- This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18.
- 分子量
- 45.7 kDa
- 基因ID
- 95
- NCBI登录号
- NM_000666
- HGNC
- 95
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