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CD3 抗体

Name: CD3 抗体
SKU: ABIN2704232
Availability: OutOfStock

GMP Grade CD3 适用: 人 FACS 宿主: 小鼠 Monoclonal OKT3 unconjugated

FACS

Image no. 2 for anti-CD3 (CD3) antibody (ABIN2704232)

2 images

产品编号 ABIN2704232

发货至: 中国

Datasheet as PDF

抗原 See all CD3 抗体

CD3
适用
190

90

23

15

15

10

8

8

7

5

3

3

2

1
人
宿主
215

45

14

13

10
小鼠
Compatible Secondaries
克隆类型
285

8
单克隆
标记
89

33

29

23

22

11

7

7

6

5

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD3 antibody is un-conjugated
应用范围
267

81

55

44

44

40

28

23

9

9

8

7

4

3

2

2

2

2

2

2

2

1

1
Flow Cytometry (FACS)

产品特性

CD3ε is a 20kD peptide chain, which together with CD3λ, CD3δ, and CD3ζ, and a T cell receptor (α/β or γ/) form the CD3/T-cell receptor complex. It is a specific marker for T lymphocytes, NK T cells, and some thymocytes. Crosslinking of TCR initiates an intracellular signaling cascade resulting in cellular activation and proliferation. The OKT3 antibody shows potent immunosuppressive properties in vivo and has been proved effective in the treatment of renal, heart, and liver allograft rejection.

纯化方法

Purified

纯度

>95 %

质量等级

GMP Grade

免疫原

Human peripheral blood lymphocytes

克隆位点

OKT3

亚型

IgG2a kappa

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anti-CD3 (CD3) antibody
CD3 适用: 人, Non-Human Primate FACS, IP, IHC (fro), Func, CyTOF 宿主: 小鼠 Monoclonal UCHT1 unconjugated

anti-CD3 (CD3) antibody (Biotin)
CD3 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal MEM-57 Biotin

anti-CD3 (CD3) antibody (Biotin)
CD3 适用: 人, Non-Human Primate FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal UCHT1 Biotin

anti-CD3 (CD3) antibody (APC)
CD3 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal UCHT1 APC

anti-CD3 (CD3) antibody (PerCP)
CD3 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal UCHT1 PerCP

anti-CD3 (CD3) antibody (PE)
CD3 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal UCHT1 PE

限制

仅限研究用
状态

Liquid

浓度

0.5 mg/mL

缓冲液

PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C
抗原

CD3

别名

CD3 (CD3 产品)

别名

CD3 antibody, AI504783 antibody, CD3epsilon antibody, T3e antibody, cd3-gamma antibody, cd3g antibody, cd3g-a antibody, cd3g/d antibody, cd3gd antibody, t3g antibody, CD3e molecule antibody, CD3d molecule antibody, CD3 antigen, epsilon polypeptide antibody, CD3g molecule S homeolog antibody, CD3E antibody, CD3D antibody, Cd3e antibody, cd3g.S antibody

背景

CD3ε is a 20kD peptide chain, which together with CD3λ, CD3δ, and CD3ζ, and a T cell receptor (α/β or γ/) form the CD3/T-cell receptor complex. It is a specific marker for T lymphocytes, NK T cells, and some thymocytes. Crosslinking of TCR initiates an intracellular signaling cascade resulting in cellular activation and proliferation. The OKT3 antibody shows potent immunosuppressive properties in vivo and has been proved effective in the treatment of renal, heart, and liver allograft rejection.

NCBI登录号

NM_000733

UniProt

P07766

途径

TCR Signaling, Ubiquitin Proteasome Pathway