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AIM2 抗体 (AA 255-354) (PE)

AIM2 适用: 人, 小鼠, 大鼠 WB, FACS 宿主: 兔 Polyclonal PE
产品编号 ABIN2690017
发货至: 中国
  • 抗原 See all AIM2 抗体
    AIM2 (Absent in Melanoma 2 (AIM2))
    抗原表位
    • 15
    • 10
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 255-354
    适用
    • 67
    • 23
    • 17
    • 3
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 55
    • 11
    • 2
    克隆类型
    • 60
    • 8
    多克隆
    标记
    • 38
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AIM2 antibody is conjugated to PE
    应用范围
    • 62
    • 34
    • 31
    • 22
    • 13
    • 13
    • 13
    • 9
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from mouse AIM2
    亚型
    IgG
    Top Product
    Discover our top product AIM2 Primary Antibody
  • 应用备注
    FCM 1:20-100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    AIM2 (Absent in Melanoma 2 (AIM2))
    别名
    AIM2 (AIM2 产品)
    别名
    AIM2 antibody, PYHIN4 antibody, Gm1313 antibody, Ifi210 antibody, absent in melanoma 2 antibody, AIM2 antibody, Aim2 antibody
    背景

    Synonyms: Gm1313, Ifi210, Interferon-inducible protein AIM2, Interferon-inducible protein 210, Ifi-210, Interferon-inducible protein p210, Aim2

    Background: Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8.

    基因ID
    383619
    UniProt
    Q91VJ1
    途径
    Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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