AIM2 抗体 (AA 255-354) (PE)
Quick Overview for AIM2 抗体 (AA 255-354) (PE) (ABIN2690017)
抗原
See all AIM2 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- AA 255-354
- 
                                            交叉反应
- 人, 小鼠, 大鼠
- 
                                            纯化方法
- Purified by Protein A.
- 
                                            免疫原
- KLH conjugated synthetic peptide derived from mouse AIM2
- 
                                            亚型
- IgG
 
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- 
    - 
                                            应用备注
- FCM 1:20-100
- 
                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
- 
                                            浓度
- 1 μg/μL
- 
                                            缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 
                                            储存液
- ProClin
- 
                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 
                                            储存条件
- -20 °C
- 
                                            储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 
                                            有效期
- 12 months
 
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    - AIM2 (Absent in Melanoma 2 (AIM2))
- 
                                            别名
- AIM2
- 
                                            背景
- 
                        Synonyms: Gm1313, Ifi210, Interferon-inducible protein AIM2, Interferon-inducible protein 210, Ifi-210, Interferon-inducible protein p210, Aim2 Background: Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8. 
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                                            基因ID
- 383619
- 
                                            UniProt
- Q91VJ1
- 
                                            途径
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
 抗原
- 
                    
 
                                     
                                     
                                    