Qa-2 抗体 (Biotin)
(3 references)Quick Overview for Qa-2 抗体 (Biotin) (ABIN2689888)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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品牌
- BD Pharmingen™
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产品特性
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The 1-1-2 antibody reacts with the Qa-2 MHC class Ib antigen, which is expressed at higher levels on mature T lymphocytes than on B cells. Its expression is upregulated in the late stages of T-cell maturation. Qa-2 is a 40 kDa GPI-linked cell surface molecule encoded by the Q5, Q6, Q7, and/or Q9 genes of the H-2 complex. A 39 kDa soluble form results from alternative splicing of the transcript. Although Qa-2 is nonpolymorphic, its level of expression on both T and B lymphocytes varies among inbred mouse strains. High expressors include strains carrying the H-2[b] haplotype low expressors include H-2[d] strains, and H-2[k] strains are Qa-2-negative.
BD Pharmingen™ Biotin Mouse Anti-Mouse Qa-2 - Biotin - Clone 1-1-2 - Isotype Mouse IgG2a, κ - Reactivity Ms - 0.1 mg -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- C3H.SW mouse skin graft and splenocytes
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亚型
- IgG2a kappa
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anti-Qa-2 antibody (PE)
适用: 小鼠 FACS 宿主: 小鼠 Monoclonal 695H1-9-9 PE
anti-Qa-2 antibody适用: 小鼠 FACS 宿主: 小鼠 Monoclonal 695H1-9-9 unconjugated
anti-Qa-2 antibody (Biotin)适用: 小鼠 FACS 宿主: 小鼠 Monoclonal 695H1-9-9 Biotin
anti-Qa-2 antibody (FITC)适用: 小鼠 FACS 宿主: 小鼠 Monoclonal 695H1-9-9 FITC
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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: "Recent thymic emigrants are distinct from most medullary thymocytes." in: European journal of immunology, Vol. 27, Issue 8, pp. 2010-5, (1997) (PubMed).
: "Antigen presentation by major histocompatibility complex class I-B molecules." in: Annual review of immunology, Vol. 12, pp. 839-80, (1994) (PubMed).
: "Epitope clusters of Qa-2 antigens defined by a panel of new monoclonal antibodies." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 142, Issue 10, pp. 3495-502, (1989) (PubMed).
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: "Recent thymic emigrants are distinct from most medullary thymocytes." in: European journal of immunology, Vol. 27, Issue 8, pp. 2010-5, (1997) (PubMed).
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- Qa-2
抗原
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