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Qa-2 抗体 (Biotin)

Cited in 3+ publications. This anti-Qa-2 antibody is a 小鼠 单克隆 antibody detecting Qa-2 in FACS 和 IHC (fro). Suitable for 小鼠.
产品编号 ABIN2689888
发货至: 中国
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Quick Overview for Qa-2 抗体 (Biotin) (ABIN2689888)

抗原

Qa-2

适用

小鼠

宿主

  • 4
小鼠

克隆类型

  • 4
单克隆

标记

  • 1
  • 1
  • 1
  • 1
This Qa-2 antibody is conjugated to Biotin

应用范围

Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

1-1
  • 产品特性

    The 1-1-2 antibody reacts with the Qa-2 MHC class Ib antigen, which is expressed at higher levels on mature T lymphocytes than on B cells. Its expression is upregulated in the late stages of T-cell maturation. Qa-2 is a 40 kDa GPI-linked cell surface molecule encoded by the Q5, Q6, Q7, and/or Q9 genes of the H-2 complex. A 39 kDa soluble form results from alternative splicing of the transcript. Although Qa-2 is nonpolymorphic, its level of expression on both T and B lymphocytes varies among inbred mouse strains. High expressors include strains carrying the H-2[b] haplotype low expressors include H-2[d] strains, and H-2[k] strains are Qa-2-negative.

    BD Pharmingen™ Biotin Mouse Anti-Mouse Qa-2 - Biotin - Clone 1-1-2 - Isotype Mouse IgG2a, κ - Reactivity Ms - 0.1 mg

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    免疫原

    C3H.SW mouse skin graft and splenocytes

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Aqueous buffered solution containing ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
  • Gabor, Godfrey, Scollay: "Recent thymic emigrants are distinct from most medullary thymocytes." in: European journal of immunology, Vol. 27, Issue 8, pp. 2010-5, (1997) (PubMed).

    Shawar, Vyas, Rodgers, Rich: "Antigen presentation by major histocompatibility complex class I-B molecules." in: Annual review of immunology, Vol. 12, pp. 839-80, (1994) (PubMed).

    Sharrow, Arn, Stroynowski, Hood, Sachs: "Epitope clusters of Qa-2 antigens defined by a panel of new monoclonal antibodies." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 142, Issue 10, pp. 3495-502, (1989) (PubMed).

  • 抗原

    Qa-2
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