LY6D 抗体
This 大鼠 单克隆 antibody specifically detects LY6D in FACS, CyTox, IHC (fro) 和 IP. It exhibits reactivity toward 小鼠. It has been mentioned in 6+ publications
(6 references)
产品编号 ABIN2689823
发货至:
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Quick Overview for LY6D 抗体 (ABIN2689823)
抗原
See all LY6D 抗体
LY6D
(Lymphocyte Antigen 6 Complex, Locus D (LY6D))
适用
小鼠
宿主
大鼠
克隆类型
单克隆
标记
This LY6D antibody is un-conjugated
应用范围
Flow Cytometry (FACS), Cytotoxicity Test (CyTox), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
克隆位点
49
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产品特性
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The 49-H4 antibody reacts with the ThB antigen (Ly-6D), which is a 15- kDa GPI-anchored protein of the Ly-6 multigene family. ThB has been detected on cortical thymocytes, small sIg- Thy-1- and sIg+ lymphoid cells in the bone marrow, thymic medullary epithelial cells, all epidermal layers (except the stratum corneum), and on peripheral B lymphocytes, but not on peripheral T lymphocytes. It has been noted that there is strain-to-strain variation in the expression of the ThB antigen on splenic B cells, those of strains with the Ly-6.2 haplotype (e.g., AKR, C57BL, DBA/2, SJL, SWR) stain more intensely with anti- ThB reagents than those of Ly-6.1 strains (e.g., A, BALB/c, CBA, C3H/He, NZB), and B cells of hybrids of Ly-6.1 and Ly-6.2 strains stain with intermediate intensity. The proportions of the ThB+ B cells and thymocytes do not differ significantly among strains.
BD Pharmingen™ Purified Rat Anti-Mouse Ly-6D - Purified - Clone 49-H4 - Isotype Rat IgG2c, κ - Reactivity Ms - 0.1 mg -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- BALB/c mouse plasmacytoma MOPC-104E
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亚型
- IgG2c kappa
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anti-Lymphocyte Antigen 6 Complex, Locus D (LY6D) (AA 21-128) antibody
LY6D 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Lymphocyte Antigen 6 Complex, Locus D (LY6D) (AA 1-128) antibodyLY6D 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C.
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: "Polymorphism at the mouse Thb locus." in: Immunogenetics, Vol. 39, Issue 6, pp. 390-4, (1994) (PubMed).
: "The thymic microenvironment." in: Immunology today, Vol. 14, Issue 9, pp. 445-59, (1993) (PubMed).
: "Isolation and characterization of cDNA clones for the mouse thymocyte B cell antigen (ThB)." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 149, Issue 8, pp. 2615-8, (1992) (PubMed).
: "The phenotypic heterogeneity of mouse thymic stromal cells." in: Immunology, Vol. 70, Issue 1, pp. 66-74, (1990) (PubMed).
: "Molecular weight determination of two genetically linked cell surface murine antigens: ThB and Ly-6." in: Immunogenetics, Vol. 15, Issue 6, pp. 591-9, (1982) (PubMed).
: "Monoclonal antibodies to ThB detect close linkage of Ly-6 and a gene regulating ThB expression." in: Immunogenetics, Vol. 11, Issue 3, pp. 275-91, (1981) (PubMed).
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: "Polymorphism at the mouse Thb locus." in: Immunogenetics, Vol. 39, Issue 6, pp. 390-4, (1994) (PubMed).
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- LY6D (Lymphocyte Antigen 6 Complex, Locus D (LY6D))
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别名
- Ly-6D
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背景
- Synonyms: ThB
抗原
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