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MHC Class II I-Ab 抗体

Cited in 4+ publications. The 小鼠 单克隆 anti-MHC Class II I-Ab antibody (Clone AF6) (ABIN2689561) specifically detects MHC Class II I-Ab in FACS. The antibody is reactive with 小鼠 samples.
产品编号 ABIN2689561
发货至: 中国
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Quick Overview for MHC Class II I-Ab 抗体 (ABIN2689561)

抗原

MHC Class II I-Ab

适用

小鼠

宿主

  • 13
  • 4
小鼠

克隆类型

  • 17
单克隆

标记

  • 7
  • 4
  • 3
  • 3
This MHC Class II I-Ab antibody is un-conjugated

应用范围

  • 17
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
Flow Cytometry (FACS)

克隆位点

AF6
  • 产品特性

    The AF6-120.1 antibody reacts with the I-A[b] MHC class II alloantigen. It cross-reacts with cells from mice of the H-2[k] and H-2[u] haplotypes. Reactivity with other haplotypes (e.g., d, f, g7, p, q, r, s) has not been observed. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature.

    BD Pharmingen™ Purified Mouse Anti-Mouse I-A[b] - Purified - Clone AF6-120.1 - Isotype Mouse IgG2a, κ - Reactivity Ms - 0.5 mg

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    免疫原

    Mouse C57BL/10J

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Aqueous buffered solution containing ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C.
  • Nabozny, Baisch, Cheng, Cosgrove, Griffiths, Luthra, David: "HLA-DQ8 transgenic mice are highly susceptible to collagen-induced arthritis: a novel model for human polyarthritis." in: The Journal of experimental medicine, Vol. 183, Issue 1, pp. 27-37, (1996) (PubMed).

    Cohn, Glimcher, Waldmann, Smith, Ben-Nun, Seidman, Choi: "Identification of functional regions on the I-Ab molecule by site-directed mutagenesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 83, Issue 3, pp. 747-51, (1986) (PubMed).

    Hattori, Buse, Jackson, Glimcher, Dorf, Minami, Makino, Moriwaki, Kuzuya, Imura: "The NOD mouse: recessive diabetogenic gene in the major histocompatibility complex." in: Science (New York, N.Y.), Vol. 231, Issue 4739, pp. 733-5, (1986) (PubMed).

    Wall, Lorber, Loken, McClatchey, Fitch: "Inhibition of proliferation of MIs- and Ia-reactive cloned T cells by a monoclonal antibody against a determinant shared by I-A and I-E." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 131, Issue 3, pp. 1056-64, (1983) (PubMed).

  • 抗原

    MHC Class II I-Ab

    别名

    I-A[b]
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