HLA-A2 抗体
This 小鼠 单克隆 antibody specifically detects HLA-A2 in FACS. It exhibits reactivity toward 人.It has been mentioned in 1 publication
(1 reference)
产品编号 ABIN2689550
发货至:
中国
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Quick Overview for HLA-A2 抗体 (ABIN2689550)
抗原
HLA-A2
适用
人
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
Flow Cytometry (FACS)
克隆位点
BB7-2
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产品特性
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The monoclonal antibody BB7.2 reacts with a subunit of the human leukocyte antigen-A2 (HLA-A2), a class I molecule of the major histocompatibility complex (MHC). The MHC gene locus encodes a group of highly polymorphic, cell-surface proteins that play a broad role in the immune response to protein antigens. MHC molecules function by binding and presenting small antigenic protein fragments to antigen-specific receptors expressed by T cells (TCR). Human (human leukocyte antigen/HLA) MHC molecules comprise two major classes, MHC class I and class II. Functionally, class I MHC molecules can bind peptides derived from intracellular antigens (eg, viral and some bacterial antigens) that are specifically recognized by CD8+ T cells, and class II MHC molecules recognize antigens derived from pathogens multiplying in intracellular vesicles, and those derived from ingested extracellular bacteria. When presented on the cell surface by the MHC class II molecules, these antigens are recognized by CD4+ T cells. TCR recognize both processed peptides bound to MHC, as well as regions of the MHC molecule itself. CD4 and CD8 accessory molecules strengthen formation of the TCR-MHC complex through their interaction with non-polymorphic regions of the MHC molecule. Profile of peripheral blood lymphocytes analyzed by flow cytometry. Second step staining with Cat. No.55988.
BD Pharmingen™ Purified Mouse Anti-Human HLA-A2 - Purified - Clone BB7.2 - Isotype Mouse IgG2b, κ - Reactivity Hu - 0.1 mg -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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亚型
- IgG2b kappa
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anti-HLA-A2 antibody (PE)
适用: 人 FACS 宿主: 小鼠 Monoclonal BB7-2 PE
anti-HLA-A2 antibody适用: 人 FACS, IP 宿主: 小鼠 Monoclonal BB7-2 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C.
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: "The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens." in: Nature, Vol. 329, Issue 6139, pp. 512-8, (1987) (PubMed).
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- HLA-A2
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物质类
- Influenza Protein
抗原
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