TCR gamma/delta 抗体
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北京 101111
Quick Overview for TCR gamma/delta 抗体 (ABIN2689517)
抗原
适用
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克隆类型
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应用范围
克隆位点
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产品特性
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The UC7-13D5 antibody reacts with the γδ T-cell Receptor (TCR) complex on γδ TCR-expressing T lymphocytes and NK-T cells of all mouse strains tested. It does not react with the αβ TCR-bearing T cells. In the mouse, cell expressing the γδ TCR are found in the thymus, intestinal epithelium, epidermis, dermis, pulmonary epithelium, peritoneum, liver, and peripheral lymphoid organs. Plate-bound UC7-13D5 antibody activates γδ TCR-bearing T cells, and in vivo administration of the mAb depletes peripheral γδ TCR-bearing T cells. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature.
BD Pharmingen™ Purified Hamster Anti-Mouse γδ T-Cell Receptor - Purified - Clone UC7-13D5 - Isotype Armenian Hamster IgG3, κ - Reactivity Ms - 0.5 mg -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Not Reported
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亚型
- IgG3 kappa
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anti-T-Cell Receptor gamma/delta (TCR gamma/delta) antibody
TCR gamma/delta 适用: 大鼠 FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal V65 unconjugated
anti-T-Cell Receptor gamma/delta (TCR gamma/delta) antibody (FITC)TCR gamma/delta 适用: 人 FACS 宿主: 小鼠 Monoclonal 11F2 FITC
anti-T-Cell Receptor gamma/delta (TCR gamma/delta) antibody (PE)TCR gamma/delta 适用: 人 FACS 宿主: 小鼠 Monoclonal 11F2 PE
anti-T-Cell Receptor gamma/delta (TCR gamma/delta) antibody (APC)TCR gamma/delta 适用: 人 FACS 宿主: 小鼠 Monoclonal 11F2 APC
anti-T-Cell Receptor gamma/delta (TCR gamma/delta) antibody (PE)TCR gamma/delta 适用: 大鼠 FACS 宿主: 小鼠 Monoclonal V65 PE
anti-T-Cell Receptor gamma/delta (TCR gamma/delta) antibodyTCR gamma/delta 适用: 大鼠 FACS, IP, IHC (fro), Func 宿主: 小鼠 Monoclonal V65 unconjugated
anti-T-Cell Receptor gamma/delta (TCR gamma/delta) antibodyTCR gamma/delta 适用: 人 FACS, IP, IHC (fro), ELISA 宿主: 小鼠 Monoclonal 11F2 unconjugated
anti-T-Cell Receptor gamma/delta (TCR gamma/delta) antibodyTCR gamma/delta 适用: 人, Non-Human Primate FACS, IHC (fro), Func, IHC (p) 宿主: 小鼠 Monoclonal B1 unconjugated
anti-T-Cell Receptor gamma/delta (TCR gamma/delta) antibodyTCR gamma/delta 适用: 人, Non-Human Primate FACS, IHC (fro), IHC (p) 宿主: 小鼠 Monoclonal B1 unconjugated
anti-T-Cell Receptor gamma/delta (TCR gamma/delta) antibody (FITC)TCR gamma/delta 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal B1 FITC
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Aqueous buffered solution containing protein stabilizer and ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C.
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: "Cutting edge: protective response to pulmonary injury requires gamma delta T lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 9, pp. 5033-6, (1999) (PubMed).
: "Functional and phenotypical characteristics of hepatic NK-like T cells in NK1.1-positive and -negative mouse strains." in: European journal of immunology, Vol. 29, Issue 6, pp. 1871-8, (1999) (PubMed).
: "Identification and characterization of novel dermal Thy-1 antigen-bearing dendritic cells in murine skin." in: The Journal of investigative dermatology, Vol. 106, Issue 3, pp. 571-5, (1996) (PubMed).
: "Gamma delta T cells function in cell-mediated immunity to acute blood-stage Plasmodium chabaudi adami malaria." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 8, pp. 3985-90, (1995) (PubMed).
: "Crosstalk between alpha/beta T cells and gamma/delta T cells in vivo: activation of alpha/beta T-cell responses after gamma/delta T-cell modulation with the monoclonal antibody GL3." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 20, pp. 9620-4, (1993) (PubMed).
: "Induction of murine peritoneal gamma/delta T cells and their role in resistance to bacterial infection." in: The Journal of experimental medicine, Vol. 178, Issue 3, pp. 971-84, (1993) (PubMed).
: "A protective role of gamma/delta T cells in primary infection with Listeria monocytogenes in mice." in: The Journal of experimental medicine, Vol. 175, Issue 1, pp. 49-56, (1992) (PubMed).
: "Repertoire development and ligand specificity of murine TCR gamma delta cells." in: Immunological reviews, Vol. 120, pp. 5-33, (1991) (PubMed).
: "Phenotypic complexity of intraepithelial lymphocytes of the small intestine." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 147, Issue 6, pp. 1746-51, (1991) (PubMed).
: "Selective expression of CD8 alpha (Ly-2) subunit on activated thymic gamma/delta cells." in: European journal of immunology, Vol. 20, Issue 4, pp. 927-30, (1990) (PubMed).
: "TCR gamma/delta+ dendritic epidermal T cells as constituents of skin-associated lymphoid tissue." in: The Journal of investigative dermatology, Vol. 94, Issue 6 Suppl, pp. 58S-63S, (1990) (PubMed).
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: "Cutting edge: protective response to pulmonary injury requires gamma delta T lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 9, pp. 5033-6, (1999) (PubMed).
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- TCR gamma/delta (T-Cell Receptor gamma/delta (TCR gamma/delta))
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别名
- Gammadelta T-Cell Receptor
抗原
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