CD90 抗体
(8 references)-
- 抗原 See all CD90 (THY1) 抗体
- CD90 (THY1)
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This CD90 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Zinc-fixed Sections) (IHC (zinc)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 品牌
- BD Pharmingen™
- 产品特性
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The G7 antibody reacts with the Thy-1.1 and Thy-1.2 alloantigens (CD90.1 and CD90.2, respectively) on thymocytes, peripheral T lymphocytes, some intraepithelial T lymphocytes (IEL, DEC), and neurons, but not B lymphocytes, of all mouse strains. CD90 is a GPI-anchored membrane glycoprotein of the Ig superfamily which is involved in signal transduction. In addition, there is evidence that CD90 mediates adhesion of thymocytes to thymic stroma. Soluble G7 mAb stimulates murine T-cell proliferation and IL-2 secretion, via signalling through the TCR/CD3 complex. mAb G7 has been reported to promote apoptosis of thymocytes and CTL clones, as determined by morphological and biochemical criteria. The Thy-1-triggered thymocyte death was found to be developmentally regulated and targeted mainly within the CD4+CD8+CD3- and CD4+CD8+CD3lo cultured immature thymocytes. G7 antibody does not react with Thy-1 (CD90) on rat thymocytes.
BD Pharmingen™ Purified Rat Anti-Mouse CD90 - Purified - Clone G7 - Isotype Rat IgG2c, κ - Reactivity Ms - 0.5 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Mouse T-cell hybridoma C 6/68
- 克隆位点
- G7
- 亚型
- IgG2c kappa
- Top Product
- Discover our top product THY1 Primary Antibody
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anti-CD90 (THY1) (AA 31-120) antibody
THY1 适用: 人, 小鼠, 大鼠, Cow, 犬, 绵羊 FACS, WB, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-CD90 (THY1) (AA 17-132) antibodyTHY1 适用: 人 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 7E1B11 unconjugated
anti-CD90 (THY1) (AA 20-133) antibodyTHY1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD90 (THY1) (AA 36-65), (N-Term) antibodyTHY1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB03970 unconjugated
anti-CD90 (THY1) antibodyTHY1 适用: 人, 猴, Baboon FACS, IHC, IP, IHC (fro), IHC (p) 宿主: 小鼠 Monoclonal 5E10 unconjugated
anti-CD90 (THY1) (AA 1-161) antibodyTHY1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F9 unconjugated
anti-CD90 (THY1) antibodyTHY1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-CD90 (THY1) (AA 20-131) antibodyTHY1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD90 (THY1) antibodyTHY1 适用: 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD90 (THY1) (Internal Region) antibodyTHY1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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: "Thy-1 triggers mouse thymocyte apoptosis through a bcl-2-resistant mechanism." in: The Journal of experimental medicine, Vol. 179, Issue 3, pp. 785-96, (1994) (PubMed).
: "Activation-driven T cell death. II. Quantitative differences alone distinguish stimuli triggering nontransformed T cell proliferation or death." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 149, Issue 5, pp. 1583-92, (1992) (PubMed).
: "Thy-1 supports adhesion of mouse thymocytes to thymic epithelial cells through a Ca2(+)-independent mechanism." in: The Journal of experimental medicine, Vol. 173, Issue 2, pp. 515-8, (1991) (PubMed).
: "Selection of T cell receptor expression mutants through the functionally linked Ly-6A." in: Cellular immunology, Vol. 130, Issue 2, pp. 271-80, (1990) (PubMed).
: "Proliferation and production of IL-2 and B cell stimulatory factor 1/IL-4 in early fetal thymocytes by activation through Thy-1 and CD3." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 140, Issue 4, pp. 1089-94, (1988) (PubMed).
: "Thy-1 functions as a signal transduction molecule in T lymphocytes and transfected B lymphocytes." in: Nature, Vol. 322, Issue 6075, pp. 181-4, (1986) (PubMed).
: "T cell-activating properties of an anti-Thy-1 monoclonal antibody. Possible analogy to OKT3/Leu-4." in: The Journal of experimental medicine, Vol. 159, Issue 3, pp. 716-30, (1984) (PubMed).
: "Neuronal cell Thy-1 glycoprotein: homology with immunoglobulin." in: Science (New York, N.Y.), Vol. 216, Issue 4547, pp. 696-703, (1982) (PubMed).
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: "Thy-1 triggers mouse thymocyte apoptosis through a bcl-2-resistant mechanism." in: The Journal of experimental medicine, Vol. 179, Issue 3, pp. 785-96, (1994) (PubMed).
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- 抗原
- CD90 (THY1)
- 别名
- CD90 (THY1 产品)
- 别名
- CD90 antibody, CD7 antibody, T25 antibody, Thy-1 antibody, Thy-1.2 antibody, Thy1.1 antibody, Thy1.2 antibody, Thy-1 cell surface antigen antibody, thymus cell antigen 1, theta antibody, THY1 antibody, Thy1 antibody
- 背景
- Synonyms: Thy-1
- 途径
- Cell-Cell Junction Organization
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