CD9 抗体 (Biotin)
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北京 101111
Quick Overview for CD9 抗体 (Biotin) (ABIN2689443)
抗原
See all CD9 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
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The KMC8 antibody reacts with CD9, a 24- kDa member of the transmembrane 4 superfamily. In the mouse, CD9 is present on bone marrow myeloid cells, stromal cells, and megakaryocyte-committed progenitors, subsets of peripheral T and B lymphocytes, and neutrophils, platelets, dendritic cells, and bone marrow-derived macrophages. CD9 has been found to be associated with integrins and other cell-surface receptors, and it is suggested to play a role in signal transduction and possibly in regulating cellular adhesive properties. It has also been demonstrated to participate in T-cell costimulation and induction of apoptosis. The KMC8 antibody has been reported to block certain CD9 functions and activate macrophages
BD Pharmingen™ Biotin Rat Anti-Mouse CD9 - Biotin - Clone KMC8 (also known as KMC 8) - Isotype Rat IgG2a, κ - Reactivity Ms - 0.1 mg -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- (C57BL/6 x DBA/2)F1 mouse bone marrow-derived stromal cell line BMS2
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亚型
- IgG2a kappa
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anti-CD9 (CD9) (AA 112-195) antibody
CD9 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 5A6D8 unconjugated
anti-CD9 (CD9) (AA 112-195) antibodyCD9 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E8H1 unconjugated
anti-CD9 (CD9) (Internal Region) antibodyCD9 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD9 (CD9) antibodyCD9 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal CD9-1619 unconjugated
anti-CD9 (CD9) antibodyCD9 适用: 人 IHC, StM, ISt 宿主: 小鼠 Monoclonal CD9-2343 unconjugated
anti-CD9 (CD9) antibodyCD9 适用: 人 FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 5G6 unconjugated
anti-CD9 (CD9) (AA 101-200) antibodyCD9 适用: 人, 小鼠, Cow, 大鼠, Pig FACS, WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-CD9 (CD9) antibody (Biotin)CD9 适用: 小鼠 FACS, WB, IP, ICC 宿主: 大鼠 Monoclonal EM-04 Biotin
anti-CD9 (CD9) antibodyCD9 适用: 人 FACS, WB, IHC (p), MS 宿主: 小鼠 Monoclonal MEM-61 unconjugated
anti-CD9 (CD9) (AA 115-145) antibodyCD9 适用: 人 FACS, WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C.
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: "Characterization of mouse clonogenic megakaryocyte progenitors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 1, pp. 205-10, (2003) (PubMed).
: "Functional association of CD9 with the Fc gamma receptors in macrophages." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 5, pp. 3256-65, (2001) (PubMed).
: "CD9 molecule expressed on stromal cells is involved in osteoclastogenesis." in: Experimental hematology, Vol. 27, Issue 5, pp. 853-9, (1999) (PubMed).
: "Differential involvement of a Fas-CPP32-like protease pathway in apoptosis of TCR/CD9-costimulated, naive T cells and TCR-restimulated, activated T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 160, Issue 12, pp. 5790-6, (1998) (PubMed).
: "Developmental pathways of dendritic cells in vivo: distinct function, phenotype, and localization of dendritic cell subsets in FLT3 ligand-treated mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 159, Issue 5, pp. 2222-31, (1997) (PubMed).
: "Antibody ligation of CD9 modifies production of myeloid cells in long-term cultures." in: Blood, Vol. 87, Issue 6, pp. 2252-61, (1996) (PubMed).
: "The ins and outs of the transmembrane 4 superfamily." in: Immunology today, Vol. 15, Issue 12, pp. 588-94, (1995) (PubMed).
: "Platelet p24/CD9, a member of the tetraspanin family of proteins." in: Annals of the New York Academy of Sciences, Vol. 714, pp. 175-84, (1994) (PubMed).
: "Monoclonal antibodies to Pgp-1/CD44 block lympho-hemopoiesis in long-term bone marrow cultures." in: The Journal of experimental medicine, Vol. 171, Issue 2, pp. 477-88, (1990) (PubMed).
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: "Characterization of mouse clonogenic megakaryocyte progenitors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 1, pp. 205-10, (2003) (PubMed).
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- CD9
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别名
- CD9
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途径
- Response to Water Deprivation, Cell-Cell Junction Organization
抗原
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