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- 抗原 See all CD58 抗体
- CD58
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适用
- 人, 犬
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD58 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 品牌
- BD Pharmingen™
- 产品特性
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Reacts with a 60-70 kDa membrane glycoprotein member of the immunoglobulin superfamily. CD58, also referred to as the lymphocyte function-associated antigen-3 (LFA-3), has a wide tissue distribution, being expressed on both hematopoietic and non-hematopoietic cells, including endothelial cells and fibroblasts. There are two isoforms of CD58: a glycosylphosphatidylinositol (GPI)-linked formed and a transmembrane form. Both isoforms may be expressed in the same cell type. Erythrocytes, however, only have the GPI-linked isoform. CD58 interacts with CD2 during cell adhesion. This binding can enhance antigen-specific T-cell activation. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood lymphocytes analyzed on a FACScan
BD Pharmingen™ Purified Mouse Anti-Human CD58 - Purified - Clone 1C3 (also known as AICD58) - Isotype Mouse IgG2a, κ - Reactivity Hu, Dog - 0.1 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 克隆位点
- 1C3
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product CD58 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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Structural and functional epitopes of the human adhesion receptor CD58 (LFA-3)." in: European journal of immunology, Vol. 22, Issue 11, pp. 2809-17, (1992) (PubMed).
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Structural and functional epitopes of the human adhesion receptor CD58 (LFA-3)." in: European journal of immunology, Vol. 22, Issue 11, pp. 2809-17, (1992) (PubMed).
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- 抗原
- CD58
- 别名
- CD58 (CD58 产品)
- 别名
- LFA-3 antibody, LFA3 antibody, ag3 antibody, CD58 molecule antibody, CD58 antibody
- 背景
- Synonyms: LFA-3
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