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CD57 抗体

There are 11+ publications for this product available. The 小鼠 单克隆 anti-CD57 antibody is suitable to detect CD57 in samples from 人. It has been validated for FACS, WB, IHC (p) 和 Func.
产品编号 ABIN2689344
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD57 抗体 (ABIN2689344)

抗原

See all CD57 (B3GAT1) 抗体
CD57 (B3GAT1) (beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD57 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func)

克隆位点

HNK
  • 产品特性

    Anti-HNK-1 monoclonal antibody recognizes a 110 kD glycoprotein (CD57) that is expressed on a subset of natural killer (NK) lymphocytes and T lymphocytes. It also recognizes epitopes on neural or neuroectodermal tumors including neurofibromas, malignant melanomas, malignant peripheral neuroectodermal tumors, Ewing's sarcomas, and small-cell lung carcinomas. Anti-HNK-1 monoclonal antibody also recognizes a carbohydrate epitope on subpopulations of several cell-adhesion molecules including N-CAM and myelin-associated glycoprotein (MAG).

    BD Pharmingen™ Purified Mouse Anti-Human CD57 - Purified - Clone HNK-1 - Isotype Mouse IgM, κ - Reactivity Hu - 0.2 mg

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    免疫原

    Membrane extracts of the HSB-2 T-lymphoblastoid cell line

    亚型

    IgM kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Aqueous buffered solution containing ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C.
  • Mechtersheimer, Staudter, Möller: "Expression of the natural killer cell-associated antigens CD56 and CD57 in human neural and striated muscle cells and in their tumors." in: Cancer research, Vol. 51, Issue 4, pp. 1300-7, (1991) (PubMed).

    Jin, Hemperly, Lloyd: "Expression of neural cell adhesion molecule in normal and neoplastic human neuroendocrine tissues." in: The American journal of pathology, Vol. 138, Issue 4, pp. 961-9, (1991) (PubMed).

    Pinto, Grant, Hayes, Schell, Parham: "Immunohistochemical expression of neuron-specific enolase and Leu 7 in Ewing's sarcoma of bone." in: Cancer, Vol. 64, Issue 6, pp. 1266-73, (1989) (PubMed).

    Schubert, Zimmermann, Cramer, Starzinski-Powitz: "Lymphocyte antigen Leu-19 as a molecular marker of regeneration in human skeletal muscle." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 1, pp. 307-11, (1989) (PubMed).

    Swanson, Manivel, Wick: "Immunoreactivity for Leu-7 in neurofibrosarcoma and other spindle cell sarcomas of soft tissue." in: The American journal of pathology, Vol. 126, Issue 3, pp. 546-60, (1987) (PubMed).

    Hemperly, Murray, Edelman, Cunningham: "Sequence of a cDNA clone encoding the polysialic acid-rich and cytoplasmic domains of the neural cell adhesion molecule N-CAM." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 83, Issue 9, pp. 3037-41, (1986) (PubMed).

    Lanier, Le, Civin, Loken, Phillips: "The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 136, Issue 12, pp. 4480-6, (1986) (PubMed).

    Manara, De Panfilis, Ferrari: "Ultrastructural characterization of human large granular lymphocyte subsets defined by the expression of HNK-1 (Leu-7), Leu-11, or both HNK-1 and Leu-11 antigens." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 33, Issue 11, pp. 1129-33, (1985) (PubMed).

    Smolle, Walter, Kerl: "Myelin-associated glycoprotein in neurogenic tumours of the skin: an immunohistological study using Leu-7 monoclonal antibody." in: Archives of dermatological research, Vol. 277, Issue 2, pp. 141-2, (1985) (PubMed).

    Lipinski, Braham, Caillaud, Carlu, Tursz: "HNK-1 antibody detects an antigen expressed on neuroectodermal cells." in: The Journal of experimental medicine, Vol. 158, Issue 5, pp. 1775-80, (1983) (PubMed).

    Lanier, Le, Phillips, Warner, Babcock: "Subpopulations of human natural killer cells defined by expression of the Leu-7 (HNK-1) and Leu-11 (NK-15) antigens." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 131, Issue 4, pp. 1789-96, (1983) (PubMed).

  • 抗原

    CD57 (B3GAT1) (beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1))

    别名

    CD57

    途径

    Glycosaminoglycan Metabolic Process
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