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CD43 抗体 (Biotin)

Name: CD43 抗体 (Biotin)
SKU: ABIN2689257
Availability: OutOfStock

This anti-CD43 antibody is a 大鼠单克隆 antibody detecting CD43 in FACS. Suitable for 小鼠. This Primary Antibody has been cited in 12+ publications.

(12 references)

产品编号 ABIN2689257

发货至: 中国

Quick Overview for CD43 抗体 (Biotin) (ABIN2689257)

抗原

See all CD43 (SPN) 抗体

CD43 (SPN) (Sialophorin (SPN))

适用

小鼠

宿主

大鼠

克隆类型

单克隆

标记

This CD43 antibody is conjugated to Biotin

应用范围

Flow Cytometry (FACS)

克隆位点

Discover our top product SPN Primary Antibody

品牌

BD Pharmingen™

产品特性

The S7 antibody reacts with the 115 kDa glycoform of CD43 (Ly-48, Leukosialin) which is expressed on IL-7-responsive pro-B cells, plasma cells, peritoneal and splenic CD5+ B cells (B-1 cells), granulocytes, monocytes, macrophages, platelets, natural killer cells, thymocytes, peripheral T cytotoxic/suppressor cells, and most T helper cells, but not resting conventional peripheral B cells. CD43 expression has also been detected on pluripotent hematopoietic stem cells and myeloid, lymphoid, and NK-cell progenitors in the bone marrow. Studies of CD43-deficient mice indicate that CD43 participates in the negative regulation of T-cell activation and adhesion. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature.

BD Pharmingen™ Biotin Rat Anti-Mouse CD43 - Biotin - Clone S7 - Isotype Rat IgG2a, κ - Reactivity Ms - 0.5 mg

纯化方法

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

免疫原

Mouse Plasmacytoma MOPC-315

亚型

IgG2a kappa
anti-Sialophorin (SPN) antibody
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anti-Sialophorin (SPN) (AA 276-400) antibody
SPN 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Sialophorin (SPN) antibody
SPN 适用: 人 FACS, WB, IHC, IF, StM 宿主: 小鼠 Monoclonal rSPN-839 unconjugated Recombinant Antibody

anti-Sialophorin (SPN) antibody
SPN 适用: 人 FACS, WB, IHC, IF, StM 宿主: 兔 Monoclonal SPN-1766R unconjugated Recombinant Antibody

anti-Sialophorin (SPN) antibody
SPN 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Sialophorin (SPN) (AA 1-400) antibody
SPN 适用: 人 FACS, WB 宿主: 小鼠 Polyclonal unconjugated

anti-Sialophorin (SPN) antibody (Biotin)
SPN 适用: 人 FACS, WB, IHC (p), IP 宿主: 小鼠 Monoclonal MEM-59 Biotin

anti-Sialophorin (SPN) antibody (FITC)
SPN 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-59 FITC

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
浓度

0.5 mg/mL

缓冲液

Aqueous buffered solution containing ≤0.09 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.

储存条件

4 °C

储存方法

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Woodman, Johnston, Hickey, Teoh, Reinhardt, Poon, Kubes: "The functional paradox of CD43 in leukocyte recruitment: a study using CD43-deficient mice." in: The Journal of experimental medicine, Vol. 188, Issue 11, pp. 2181-6, (1999) (PubMed).

Stockton, Cheng, Manjunath, Ardman, von Andrian: "Negative regulation of T cell homing by CD43." in: Immunity, Vol. 8, Issue 3, pp. 373-81, (1998) (PubMed).

Thurman, Walker, Jayaraman, Manjunath, Ardman, Green: "Regulation of in vitro and in vivo T cell activation by CD43." in: International immunology, Vol. 10, Issue 5, pp. 691-701, (1998) (PubMed).

Rolink, ten Boekel, Melchers, Fearon, Krop, Andersson: "A subpopulation of B220+ cells in murine bone marrow does not express CD19 and contains natural killer cell progenitors." in: The Journal of experimental medicine, Vol. 183, Issue 1, pp. 187-94, (1996) (PubMed).

Manjunath, Correa, Ardman, Ardman: "Negative regulation of T-cell adhesion and activation by CD43." in: Nature, Vol. 377, Issue 6549, pp. 535-8, (1995) (PubMed).

Moore, Bennett, Kumar: "Transplantable NK cell progenitors in murine bone marrow." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 4, pp. 1653-63, (1995) (PubMed).

Wells, Kantor, Stall: "CD43 (S7) expression identifies peripheral B cell subsets." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 153, Issue 12, pp. 5503-15, (1995) (PubMed).

Jones, Federsppiel, Ellies, Williams, Burgener, Duronio, Smith, Takei, Ziltener: "Characterization of the activation-associated isoform of CD43 on murine T lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 153, Issue 8, pp. 3426-39, (1994) (PubMed).

Moore, Huang, Terstappen, Bennett, Kumar: "Expression of CD43 on murine and human pluripotent hematopoietic stem cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 153, Issue 11, pp. 4978-87, (1994) (PubMed).

Hardy, Hayakawa: "Generation of Ly-1 B cells from developmentally distinct precursors. Enrichment by stromal-cell culture or cell sorting." in: Annals of the New York Academy of Sciences, Vol. 651, pp. 99-111, (1992) (PubMed).

Hardy, Carmack, Shinton, Kemp, Hayakawa: "Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow." in: The Journal of experimental medicine, Vol. 173, Issue 5, pp. 1213-25, (1991) (PubMed).

Gulley, Ogata, Thorson, Dailey, Kemp: "Identification of a murine pan-T cell antigen which is also expressed during the terminal phases of B cell differentiation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 140, Issue 11, pp. 3751-7, (1988) (PubMed).
抗原

CD43 (SPN) (Sialophorin (SPN))

别名

CD43

背景

Synonyms: Ly-48, Leukosialin

途径

Regulation of Leukocyte Mediated Immunity