Integrin Alpha2b 抗体
(5 references)-
- 抗原 See all Integrin Alpha2b (CD41) 抗体
- Integrin Alpha2b (CD41)
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This Integrin Alpha2b antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Cytotoxicity Test (CyTox)
- 品牌
- BD Pharmingen™
- 产品特性
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The MWReg30 antibody reacts with glycoprotein (gp) IIb, also called integrin αIIb chain (CD41), that associates with integrin β3 chain (gpIIIa or CD61) to form the gpIIb/IIIa (CD41/CD61) complex. CD41/CD61 is expressed on platelets, megakaryocytes, and early hematopoietic progenitors. The integrin complex binds to fibrinogen, fibronectin, vitronectin, von Willebrand factor, and thrombospondin. It is important for platelet adhesion and aggregation, and it may play a role in osteolytic tumor metastasis. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature.
BD Pharmingen™ Purified Rat Anti-Mouse CD41 - Purified - Clone MWReg30 - Isotype Rat IgG1, κ - Reactivity Ms - 0.5 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Mouse Platelets
- 克隆位点
- MWReg30
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CD41 Primary Antibody
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anti-Integrin Alpha2b (CD41) (AA 45-149) antibody
CD41 适用: 人 FACS, WB, ELISA, IHC 宿主: 小鼠 Monoclonal 2E10C9 unconjugated
anti-Integrin Alpha2b (CD41) (AA 351-450) antibodyCD41 适用: 人, 大鼠 FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin Alpha2b (CD41) (Internal Region) antibodyCD41 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 适用: 小鼠 FACS, ELISA, IHC (fro), IP, IHC (p), Func 宿主: 大鼠 Monoclonal MWReg30 unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 适用: 小鼠 FACS, ELISA, IHC (fro), IP, IHC (p) 宿主: 大鼠 Monoclonal MWReg30 unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 适用: 人, Non-Human Primate FACS, IHC (fro) 宿主: 小鼠 Monoclonal HIP2 unconjugated
anti-Integrin Alpha2b (CD41) antibody (Biotin)CD41 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-06 Biotin
anti-Integrin Alpha2b (CD41) antibody (FITC)CD41 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-06 FITC
anti-Integrin Alpha2b (CD41) (AA 677-711), (C-Term) antibodyCD41 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin Alpha2b (CD41) (AA 639-887) antibodyCD41 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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: "Platelet and osteoclast beta3 integrins are critical for bone metastasis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 24, pp. 14205-10, (2003) (PubMed).
: "CD41 expression defines the onset of primitive and definitive hematopoiesis in the murine embryo." in: Development (Cambridge, England), Vol. 130, Issue 18, pp. 4393-403, (2003) (PubMed).
: "Acute systemic reaction and lung alterations induced by an antiplatelet integrin gpIIb/IIIa antibody in mice." in: Blood, Vol. 94, Issue 2, pp. 684-93, (1999) (PubMed).
: "Platelet membrane glycoproteins: functions in cellular interactions." in: Annual review of cell biology, Vol. 6, pp. 329-57, (1991) (PubMed).
: "GPIIb-IIIa: the responsive integrin." in: Cell, Vol. 65, Issue 3, pp. 359-62, (1991) (PubMed).
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: "Platelet and osteoclast beta3 integrins are critical for bone metastasis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 24, pp. 14205-10, (2003) (PubMed).
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- 抗原
- Integrin Alpha2b (CD41)
- 别名
- CD41 (CD41 产品)
- 别名
- AI172977 antibody, CD41 antibody, CD41B antibody, GpIIb antibody, alphaIIb antibody, BDPLT16 antibody, BDPLT2 antibody, GP2B antibody, GPIIb antibody, GT antibody, GTA antibody, HPA3 antibody, integrin alpha 2b antibody, integrin subunit alpha 2b antibody, Itga2b antibody, ITGA2B antibody
- 背景
- Synonyms: Integrin α IIb chain
- 途径
- Integrin Complex
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