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ITGB1 抗体

This anti-ITGB1 antibody is a Armenian Hamster 单克隆 antibody detecting ITGB1 in FACS, IHC (fro) 和 IHC (f). Suitable for 小鼠 和 大鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN2689157
发货至: 中国

Quick Overview for ITGB1 抗体 (ABIN2689157)

抗原

See all ITGB1 抗体
ITGB1 (Integrin beta 1 (ITGB1))

适用

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小鼠, 大鼠

宿主

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Armenian Hamster

克隆类型

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单克隆

标记

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This ITGB1 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

HM beta1
  • 品牌

    BD Pharmingen™

    产品特性

    The HM β1-1 monoclonal antibody specifically binds to the 130- kDa integrin β1 chain (CD29). CD29 is expressed on the cell surface as a heterodimer with one of the distinct integrin-α chains. With α1 through α6 (CD49a through CD49f), it forms the VLA-1 through VLA-6 complexes, respectively, and with αv (CD51), it forms αvβ1 integrin. It also associates with the integrin α7 α8, and α9 chains in non-lymphoid tissues. As a result, CD29 has a broad tissue distribution, including lymphocytes, endothelia, smooth muscle, epithelia, and oocytes. This hamster mAb to a mouse leukocyte antigen has been observed to crossreact with similar populations of rat leukocytes. Source of the immunogen was purified mouse VLA-4 (α4β1, CD49d/CD29). Immunohistochemical staining of CD29 positive cells. Frozen sections of normal mouse spleen were stained with Purified Hamster Anti-Mouse CD29 (Cat. No. 550530) antibody. Endothelial cells of the central arteriole and splenic sinuses can be identified by the brown labeling of their cell membranes. Amplification 20X.

    BD Pharmingen™ Purified Hamster Anti-Mouse CD29 - Purified - Clone HM β1-1 - Isotype Armenian Hamster IgG2, λ1 - Reactivity Ms, Rat - 1 mL

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    免疫原

    Purified mouse VLA-4

    亚型

    IgG2 lambda
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    15.625 μg/mL

    缓冲液

    Aqueous buffered solution containing BSA, goat serum, and ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C.
  • Noto, Kato, Okumura, Yagita: "Identification and functional characterization of mouse CD29 with a mAb." in: International immunology, Vol. 7, Issue 5, pp. 835-42, (1995) (PubMed).

    Springer: "Adhesion receptors of the immune system." in: Nature, Vol. 346, Issue 6283, pp. 425-34, (1990) (PubMed).

  • 抗原

    ITGB1 (Integrin beta 1 (ITGB1))

    别名

    CD29

    背景

    Synonyms: Itgb1, Integrin beta-1, Fnrb, gpIIa, VLA-4 subunit beta

    途径

    Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome
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