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ITGB1 抗体

Cited in 3+ publications. This anti-ITGB1 antibody is a Armenian Hamster 单克隆 antibody detecting ITGB1 in FACS, IP 和 BR. Suitable for 小鼠 和 大鼠.
产品编号 ABIN2689153
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ITGB1 抗体 (ABIN2689153)

抗原

See all ITGB1 抗体
ITGB1 (Integrin beta 1 (ITGB1))

适用

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小鼠, 大鼠

宿主

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Armenian Hamster

克隆类型

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单克隆

标记

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This ITGB1 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP), Blocking Reagent (BR)

克隆位点

HM beta1
  • 产品特性

    The HMβ1-1 antibody reacts with the 130- kDa integrin β1 chain (CD29). CD29 is expressed on the cell surface as a heterodimer with one of the distinct integrin-α chains. With α1 through α6(CD49a through CD49f), it forms the VLA-1 through VLA-6 complexes, respectively, and with αv (CD51), it forms αvβ1 integrin. It also associates with the integrin α7 α8, and α9 chains in non-lymphoid tissues. As a result, CD29 has a broad tissue distribution, including lymphocytes, endothelia, smooth muscle, epithelia, and oocytes. This hamster mAb to a mouse leukocyte antigen has been observed to cross-react with similar populations of rat leukocytes. Source of the immunogen was purified mouse VLA-4 (α4β1, CD49d/CD29).

    BD Pharmingen™ Purified Armenian Hamster Anti-Mouse CD29 - Purified - Clone HM β1-1 - Isotype Armenian Hamster IgG2, λ1 - Reactivity Ms, Rat - 0.5 mg

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    免疫原

    Purified mouse VLA-4

    亚型

    IgG2 lambda
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Aqueous buffered solution containing ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C.
  • Noto, Kato, Okumura, Yagita: "Identification and functional characterization of mouse CD29 with a mAb." in: International immunology, Vol. 7, Issue 5, pp. 835-42, (1995) (PubMed).

    Mendrick, Kelly: "Temporal expression of VLA-2 and modulation of its ligand specificity by rat glomerular epithelial cells in vitro." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 69, Issue 6, pp. 690-702, (1994) (PubMed).

    Springer: "Adhesion receptors of the immune system." in: Nature, Vol. 346, Issue 6283, pp. 425-34, (1990) (PubMed).

  • 抗原

    ITGB1 (Integrin beta 1 (ITGB1))

    别名

    CD29

    背景

    Synonyms: Integrin β1 chain

    途径

    Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome
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