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LY75/DEC-205 抗体

Cited in 3+ publications. This 小鼠 单克隆 anti-LY75/DEC-205 antibody (Clone MG38) specifically detects LY75/DEC-205 in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN2689082
发货至: 中国
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Quick Overview for LY75/DEC-205 抗体 (ABIN2689082)

抗原

See all LY75/DEC-205 (LY75) 抗体
LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))

适用

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宿主

  • 50
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小鼠

克隆类型

  • 64
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  • 2
单克隆

标记

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This LY75/DEC-205 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

MG38
  • 产品特性

    Reacts with DEC-205, a 205 kDa transmembrane protein with C-type lectin external domains, present on dendritic cells (DC) and some epithelia. It is being described as a multilectin receptor for adsorptive endocytosis. MG38 antibody reacted with mature monocyte-derived DC and also with B cells, monocytes and weakly on T cells and NK cells. Antibody MG38 is useful for the study of DC development. Profile of CD205 (DEC-205), clone MG38, reactivity on monocyte-derived cultured dendritic cells analyzed by flow cytometry. Second step staining with FITC Goat Anti-Mouse IgG/IgM (Cat. No. 555988).

    BD Pharmingen™ Purified Mouse Anti-Human CD205 - Purified - Clone MG38 - Isotype Mouse IgG2b - Reactivity Hu - 0.1 mg

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Aqueous buffered solution containing ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C.
  • Guo, Gong, Maric, Misulovin, Pack, Mahnke, Nussenzweig, Steinman: "A monoclonal antibody to the DEC-205 endocytosis receptor on human dendritic cells." in: Human immunology, Vol. 61, Issue 8, pp. 729-38, (2000) (PubMed).

    Kato, Neil, Fearnley, McLellan, Vuckovic, Hart: "Expression of multilectin receptors and comparative FITC-dextran uptake by human dendritic cells." in: International immunology, Vol. 12, Issue 11, pp. 1511-9, (2000) (PubMed).

    Kato, Neil, Clark, Morris, Sorg, Hart: "cDNA cloning of human DEC-205, a putative antigen-uptake receptor on dendritic cells." in: Immunogenetics, Vol. 47, Issue 6, pp. 442-50, (1998) (PubMed).

  • 抗原

    LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))

    别名

    CD205

    背景

    Synonyms: DEC-205, Lymphocyte Antigen 75, CLEC13B
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