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PROCR 抗体

There are 2+ publications for this product available. The 大鼠 单克隆 anti-PROCR antibody is suitable to detect PROCR in samples from 人. It has been validated for FACS.
产品编号 ABIN2689080
发货至: 中国
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Quick Overview for PROCR 抗体 (ABIN2689080)

抗原

See all PROCR 抗体
PROCR (Protein C Receptor, Endothelial (PROCR))

适用

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宿主

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大鼠

克隆类型

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单克隆

标记

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This PROCR antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

RCR
  • 产品特性

    Reacts with endothelial cell protein C receptor (EPCR), a 25 kDa, type I transmembrane glycoprotein, expressed on endothelial cells in arteries, veins and capillaries. EPCR is also referred to as CD201. It binds protein C and augments its activation. Reports indicate that EPCR is expressed on several malignant cell lines. Malignant cell lines that express EPCR also show significant levels of protein C activation and this activation could be inhibited by anti-EPCR antibody. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of anti-CD201 (RCR-252) reactivity on ECV304 cells analyzed by flow cytometry. Second step staining with Cat. No. 554016.

    BD Pharmingen™ Purified Rat Anti-Human CD201 - Purified - Clone RCR-252 - Isotype Rat IgG1, κ - Reactivity Hu - 0.1 mg

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Aqueous buffered solution containing ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C.
  • Biguzzi, Merati, Liaw, Bucciarelli, Oganesyan, Qu, Gu, Fetiveau, Esmon, Mannucci, Faioni: "A 23bp insertion in the endothelial protein C receptor (EPCR) gene impairs EPCR function." in: Thrombosis and haemostasis, Vol. 86, Issue 4, pp. 945-8, (2001) (PubMed).

    Tsuneyoshi, Fukudome, Horiguchi, Ye, Matsuzaki, Toi, Suzuki, Kimoto: "Expression and anticoagulant function of the endothelial cell protein C receptor (EPCR) in cancer cell lines." in: Thrombosis and haemostasis, Vol. 85, Issue 2, pp. 356-61, (2001) (PubMed).

  • 抗原

    PROCR (Protein C Receptor, Endothelial (PROCR))

    别名

    CD201

    背景

    Synonyms: EPCR
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