PROCR 抗体
Quick Overview for PROCR 抗体 (ABIN2689080)
抗原
See all PROCR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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品牌
- BD Pharmingen™
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产品特性
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Reacts with endothelial cell protein C receptor (EPCR), a 25 kDa, type I transmembrane glycoprotein, expressed on endothelial cells in arteries, veins and capillaries. EPCR is also referred to as CD201. It binds protein C and augments its activation. Reports indicate that EPCR is expressed on several malignant cell lines. Malignant cell lines that express EPCR also show significant levels of protein C activation and this activation could be inhibited by anti-EPCR antibody. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of anti-CD201 (RCR-252) reactivity on ECV304 cells analyzed by flow cytometry. Second step staining with Cat. No. 554016.
BD Pharmingen™ Purified Rat Anti-Human CD201 - Purified - Clone RCR-252 - Isotype Rat IgG1, κ - Reactivity Hu - 0.1 mg -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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亚型
- IgG1 kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C.
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A 23bp insertion in the endothelial protein C receptor (EPCR) gene impairs EPCR function." in: Thrombosis and haemostasis, Vol. 86, Issue 4, pp. 945-8, (2001) (PubMed).
: "Expression and anticoagulant function of the endothelial cell protein C receptor (EPCR) in cancer cell lines." in: Thrombosis and haemostasis, Vol. 85, Issue 2, pp. 356-61, (2001) (PubMed).
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A 23bp insertion in the endothelial protein C receptor (EPCR) gene impairs EPCR function." in: Thrombosis and haemostasis, Vol. 86, Issue 4, pp. 945-8, (2001) (PubMed).
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- PROCR (Protein C Receptor, Endothelial (PROCR))
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别名
- CD201
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背景
- Synonyms: EPCR
抗原
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