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CD1d 抗体

Cited in 2+ publications. This anti-CD1d antibody is a 小鼠 单克隆 antibody detecting CD1d in FACS. Suitable for 人.
产品编号 ABIN2689065
发货至: 中国
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Room 801-803
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Quick Overview for CD1d 抗体 (ABIN2689065)

抗原

See all CD1d (CD1D) 抗体
CD1d (CD1D) (CD1d Molecule (CD1D))

适用

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宿主

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小鼠

克隆类型

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  • 1
单克隆

标记

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This CD1d antibody is un-conjugated

应用范围

  • 42
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Flow Cytometry (FACS)

克隆位点

CD1d42
  • 产品特性

    Reacts with a glycosylated type I transmembrane α chain (43-49 kDa) non- covalently associated with β2-microglobulin. CD1d is a member of the CD1 family of molecules, which belong to the immunoglobulin superfamily. Sequence homology data classifies the CD1 Molecules into two groups. Group 1 includes CD1a, CD1b and CD1c molecules, group 2 includes CD1d molecules and their homologues in other species. CD1d is expressed on human intestinal epithelial cells (IEC). CD1d42 monoclonal antibody reacts with peripheral blood B cells coexpressing CD19 and CD45RA. It is not seen on CD3[+], or CD45RO[+] cells. Studies suggest that CD1d participates in lipid antigen presentation. Profile of peripheral blood lymphocytes analyzed by flow cytometry

    BD Pharmingen™ Purified Mouse Anti-Human CD1d - Purified - Clone CD1d42 (also known as 42.1) - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Aqueous buffered solution containing ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C.
  • Hong, Scherer, Singh, Mendiratta, Serizawa, Koezuka, Van Kaer: "Lipid antigen presentation in the immune system: lessons learned from CD1d knockout mice." in: Immunological reviews, Vol. 169, pp. 31-44, (1999) (PubMed).

    Somnay-Wadgaonkar, Nusrat, Kim, Canchis, Balk, Colgan, Blumberg: "Immunolocalization of CD1d in human intestinal epithelial cells and identification of a beta2-microglobulin-associated form." in: International immunology, Vol. 11, Issue 3, pp. 383-92, (1999) (PubMed).

  • 抗原

    CD1d (CD1D) (CD1d Molecule (CD1D))

    别名

    CD1d

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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