CD1d 抗体
Quick Overview for CD1d 抗体 (ABIN2689065)
抗原
See all CD1d (CD1D) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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品牌
- BD Pharmingen™
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产品特性
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Reacts with a glycosylated type I transmembrane α chain (43-49 kDa) non- covalently associated with β2-microglobulin. CD1d is a member of the CD1 family of molecules, which belong to the immunoglobulin superfamily. Sequence homology data classifies the CD1 Molecules into two groups. Group 1 includes CD1a, CD1b and CD1c molecules, group 2 includes CD1d molecules and their homologues in other species. CD1d is expressed on human intestinal epithelial cells (IEC). CD1d42 monoclonal antibody reacts with peripheral blood B cells coexpressing CD19 and CD45RA. It is not seen on CD3[+], or CD45RO[+] cells. Studies suggest that CD1d participates in lipid antigen presentation. Profile of peripheral blood lymphocytes analyzed by flow cytometry
BD Pharmingen™ Purified Mouse Anti-Human CD1d - Purified - Clone CD1d42 (also known as 42.1) - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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亚型
- IgG1 kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C.
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: "Lipid antigen presentation in the immune system: lessons learned from CD1d knockout mice." in: Immunological reviews, Vol. 169, pp. 31-44, (1999) (PubMed).
: "Immunolocalization of CD1d in human intestinal epithelial cells and identification of a beta2-microglobulin-associated form." in: International immunology, Vol. 11, Issue 3, pp. 383-92, (1999) (PubMed).
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: "Lipid antigen presentation in the immune system: lessons learned from CD1d knockout mice." in: Immunological reviews, Vol. 169, pp. 31-44, (1999) (PubMed).
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- CD1d (CD1D) (CD1d Molecule (CD1D))
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别名
- CD1d
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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