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CD19 抗体

There are 4+ publications for this product available. The 小鼠 单克隆 anti-CD19 antibody is suitable to detect CD19 in samples from 人. It has been validated for FACS, IHC (fro) 和 FM.
产品编号 ABIN2689047
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD19 抗体 (ABIN2689047)

抗原

See all CD19 抗体
CD19 (CD19 Molecule (CD19))

适用

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小鼠

克隆类型

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单克隆

标记

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This CD19 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Fluorescence Microscopy (FM)

克隆位点

HIB19
  • 产品特性

    Reacts with the 95 kDa type I transmembrane glycoprotein expressed during all stages of B-cell differentiation and maturation, except on plasma cells. CD19 is also present on follicular dendritic cells. It is not found on T cells or on normal granulocytes. CD19 plays a role in regulation of B-cell proliferation. It associates with the complement receptor 2 (CD21), TAPA-1 (CD81), Leu 13, and/or MHC class II to form a signal transduction complex on the surface of B cells. Anti-CD19 clone HIB19 partially blocks clone B43, another C19 mAb. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood lymphocytes analyzed on a FACScan

    BD Pharmingen™ Purified Mouse Anti-Human CD19 - Purified - Clone HIB19 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Aqueous buffered solution containing ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C.
  • Bradbury, Goldmacher, Tedder: "The CD19 signal transduction complex of B lymphocytes. Deletion of the CD19 cytoplasmic domain alters signal transduction but not complex formation with TAPA-1 and Leu 13." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 151, Issue 6, pp. 2915-27, (1993) (PubMed).

    Favaloro, Moraitis, Koutts, Exner, Bradstock: "Endothelial cells and normal circulating haemopoietic cells share a number of surface antigens." in: Thrombosis and haemostasis, Vol. 61, Issue 2, pp. 217-24, (1989) (PubMed).

    Uckun, Muraguchi, Ledbetter, Kishimoto, OBrien, Roloff, Gajl-Peczalska, Provisor, Koller: "Biphenotypic leukemic lymphocyte precursors in CD2+CD19+ acute lymphoblastic leukemia and their putative normal counterparts in human fetal hematopoietic tissues." in: Blood, Vol. 73, Issue 4, pp. 1000-15, (1989) (PubMed).

    Nadler, Anderson, Marti, Bates, Park, Daley, Schlossman: "B4, a human B lymphocyte-associated antigen expressed on normal, mitogen-activated, and malignant B lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 131, Issue 1, pp. 244-50, (1983) (PubMed).

  • 抗原

    CD19 (CD19 Molecule (CD19))

    别名

    CD19

    途径

    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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