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CD16 抗体 (Biotin)

This anti-CD16 antibody is a 小鼠 单克隆 antibody detecting CD16 in FACS. Suitable for 猕猴, Cynomolgus 和 Baboon. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN2689004
发货至: 中国

Quick Overview for CD16 抗体 (Biotin) (ABIN2689004)

抗原

See all CD16 抗体
CD16

适用

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猕猴, Cynomolgus, Baboon

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD16 antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS)

克隆位点

3G8
  • 品牌

    BD Pharmingen™

    产品特性

    Reacts with the 50-65 kDa transmembrane form of IgG Fc (FcγRIII), a human NK-cell-associated antigen. CD16 is expressed on NK cells as well as macrophages and granulocytes. Reports indicate that CD16 plays a role in signal transduction and NK cell activation. CD16 antibody blocks the binding of soluble immune complexes to granulocytes. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood lymphocytes analyzed on a FACScan

    BD Pharmingen™ Biotin Mouse Anti-Human CD16 - Biotin - Clone 3G8 - Isotype Mouse IgG1, κ - Reactivity Bab, Cyno, Rhe - 100 Tests

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    样本量

    20 μL

    限制

    仅限研究用
  • 缓冲液

    Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
  • Wirthmueller, Kurosaki, Murakami, Ravetch: "Signal transduction by Fc gamma RIII (CD16) is mediated through the gamma chain." in: The Journal of experimental medicine, Vol. 175, Issue 5, pp. 1381-90, (1992) (PubMed).

    Stroncek, Skubitz, Plachta, Shankar, Clay, Herman, Fleit, McCullough: "Alloimmune neonatal neutropenia due to an antibody to the neutrophil Fc-gamma receptor III with maternal deficiency of CD16 antigen." in: Blood, Vol. 77, Issue 7, pp. 1572-80, (1991) (PubMed).

    Fleit, Wright, Unkeless: "Human neutrophil Fc gamma receptor distribution and structure." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 79, Issue 10, pp. 3275-9, (1982) (PubMed).

    Guesdon, Ternynck, Avrameas: "The use of avidin-biotin interaction in immunoenzymatic techniques." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 27, Issue 8, pp. 1131-9, (1979) (PubMed).

  • 抗原

    CD16

    别名

    CD16

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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