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- 抗原 See all BST1 抗体
- BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))
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适用
- 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This BST1 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunoaffinity Chromatography (IAC)
- 品牌
- BD Pharmingen™
- 产品特性
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The BP-3 antibody reacts with CD157, also known as the BP-3 alloantigen or Bone marrow STromal cell antigen-1 (BST-1), found in a variety of common laboratory strains of mice (AKR, BALB/c, CBA/N, C3H/HeJ, C57BL/6, DBA/2, NZB, C.B-17, SJL and Swiss, but not A/J). CD157 is a differentially glycosylated GPI-linked cell-surface glycoprotein with a core protein of 32 kDa and differing patterns of glycosylation in different types of cells. It is a member, along with CD38, of a family of genetically-related ectoenzymes. The BP-3 alloantigen is expressed on the B lineage from the earliest detectable progenitors to circulating immature B lymphocytes, on immature thymocytes up to the expression of the T-cell receptor, on circulating neutrophils, peritoneal macrophages, on subpopulations of stromal cells in peripheral lymphoid organs (but not in bone marrow or thymus), on intestinal epithelial cells, and in the lumen of kidney-collecting tubules. The distribution of CD157 antigen on leukocytes and stromal cells of lymphoid organs suggests that it may be involved in leukocyte-stroma interactions which support the development, migration, and/or responses of leukocyte populations.
BD Pharmingen™ Purified Mouse Anti-Mouse CD157 - Purified - Clone BP-3 - Isotype Mouse IgG2b, κ - Reactivity Ms - 0.1 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Mouse pre-B cell line
- 克隆位点
- BP
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product BST1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen." in: The Journal of experimental medicine, Vol. 189, Issue 2, pp. 403-12, (1999) (PubMed).
: "Deletion of bone marrow stromal cell antigen-1 (CD157) gene impaired systemic thymus independent-2 antigen-induced IgG3 and mucosal TD antigen-elicited IgA responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 8, pp. 3974-83, (1998) (PubMed).
: "Genomic organization and chromosomal localization of the mouse Bp3 gene, a member of the CD38/ADP-ribosyl cyclase family." in: Immunogenetics, Vol. 45, Issue 1, pp. 35-43, (1996) (PubMed).
: "The murine BP-3 gene encodes a relative of the CD38/NAD glycohydrolase family." in: International immunology, Vol. 6, Issue 9, pp. 1353-60, (1995) (PubMed).
: "Reticular cells in peripheral lymphoid tissues express the phosphatidylinositol-linked BP-3 antigen." in: European journal of immunology, Vol. 21, Issue 2, pp. 509-15, (1991) (PubMed).
: "BP-3 alloantigen. A cell surface glycoprotein that marks early B lineage cells and mature myeloid lineage cells in mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 141, Issue 8, pp. 2551-6, (1988) (PubMed).
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Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen." in: The Journal of experimental medicine, Vol. 189, Issue 2, pp. 403-12, (1999) (PubMed).
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- 抗原
- BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))
- 别名
- CD157 (BST1 产品)
- 别名
- BST1 antibody, 114/A10 antibody, A530073F09 antibody, BP-3 antibody, Bp3 antibody, Bsta1 antibody, CD157 antibody, Ly65 antibody, bone marrow stromal cell antigen 1 antibody, BST1 antibody, Bst1 antibody
- 背景
- Synonyms: BP-3 Alloantigen
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