(3 references)-
- 抗原 See all TNFSF8 抗体
- TNFSF8 (Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TNFSF8 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 品牌
- BD Pharmingen™
- 产品特性
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Reacts with CD30 ligand (CD153) a 40 kDa type II membrane glycoprotein expressed mainly on activated T cells, as well as on activated macrophages, neutrophils and both normal and malignant B cells. CD30 ligand is a member of the tumor necrosis factor (TNF) superfamily. In addition to TNF, this family also includes lymphotoxin α (LTα), LTβ, CD154, CD95L, CD70, CD134 ligand, CDw137 ligand, and TRAIL. Results of in vitro studies have shown that CD30 mediates a variety of activation and differentiation, or apoptotic signals. Recently, it has been reported that CD30-deficient mice have elevated numbers of thymocytes and show a gross defect in negative but not positive selection during T cell differentiation, suggesting an important role for CD30/CD30L interactions in the deletion of autoreactive T cells. Profile of PMA & CA++ ionophore- stimulated peripheral blood lymphocytes analyzed by flow cytometry
BD Pharmingen™ Purified Mouse Anti-Human CD153 - Purified - Clone D2-1173 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 克隆位点
- D2
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product TNFSF8 Primary Antibody
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anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 68-231) antibody
TNFSF8 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (Internal Region) antibodyTNFSF8 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 60-227) antibodyTNFSF8 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 153-234) antibodyTNFSF8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E11 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 63-234) antibodyTNFSF8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E1 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 153-234) antibodyTNFSF8 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) antibodyTNFSF8 适用: 小鼠 FACS, BP, Func 宿主: 兔 Chimeric RM153 unconjugated Recombinant Antibody
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 1-234) antibodyTNFSF8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 55-104) antibodyTNFSF8 适用: 人, 小鼠, Cow, 马, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 63-234) antibodyTNFSF8 适用: 人 FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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: "High CD30 ligand expression by epithelial cells and Hassal's corpuscles in the medulla of human thymus." in: Blood, Vol. 91, Issue 9, pp. 3323-32, (1998) (PubMed).
: "CD30-mediated signaling promotes the development of human T helper type 2-like T cells." in: The Journal of experimental medicine, Vol. 182, Issue 6, pp. 1655-61, (1996) (PubMed).
: "CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF." in: Cell, Vol. 73, Issue 7, pp. 1349-60, (1993) (PubMed).
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: "High CD30 ligand expression by epithelial cells and Hassal's corpuscles in the medulla of human thymus." in: Blood, Vol. 91, Issue 9, pp. 3323-32, (1998) (PubMed).
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- 抗原
- TNFSF8 (Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8))
- 别名
- CD153 (TNFSF8 产品)
- 别名
- CD153 antibody, CD30LG antibody, Cd30l antibody, CD30L antibody, TNFRSF8 antibody, TNFSF8 antibody, tumor necrosis factor (ligand) superfamily, member 8 antibody, TNF superfamily member 8 antibody, tumor necrosis factor superfamily member 8 antibody, Tnfsf8 antibody, TNFSF8 antibody
- 背景
- Synonyms: CD30L
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