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Thrombomodulin 抗体

THBD 适用: 人 FACS, IHC (fro), FM 宿主: 小鼠 Monoclonal 1A4 unconjugated
产品编号 ABIN2688974
发货至: 中国
  • 抗原 See all Thrombomodulin (THBD) 抗体
    Thrombomodulin (THBD)
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This Thrombomodulin antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Fluorescence Microscopy (FM)
    品牌
    BD Pharmingen™
    产品特性
    Reacts with a 75 kDa, a single chain, type I membrane glycoprotein referred to as thrombomodulin and fetomodulin. CD141 is expressed on endothelial cells, smooth muscle cells, epithelial cells, synovial lining cells, and keratinocytes. It is also found on megakaryocytes, peripheral blood moncytes, and neutrophils, but not on lymphocytes. Reports indicate that CD 141 plays an important role in Protein C activation and the initiation of the Protein C anticoagulant pathway. Thrombin loses its procagulant function when it binds to CD141, and the CD141/thrombin complex is able to activate Protein C. This product is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood monocytes analyzed by flow cytometry.

    BD Pharmingen™ Purified Mouse Anti-Human CD141 - Purified - Clone 1A4 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    克隆位点
    1A4
    亚型
    IgG1 kappa
    Top Product
    Discover our top product THBD Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C.
  • Teasdale, Bird, Bird: "Internalization of the anticoagulant thrombomodulin is constitutive and does not require a signal in the cytoplasmic domain." in: Immunology and cell biology, Vol. 72, Issue 6, pp. 480-8, (1995) (PubMed).

  • 抗原
    Thrombomodulin (THBD)
    别名
    CD141 (THBD 产品)
    别名
    AHUS6 antibody, BDCA3 antibody, CD141 antibody, THPH12 antibody, THRM antibody, TM antibody, AI385582 antibody, THBD antibody, HAST antibody, HAST3 antibody, M-PST antibody, ST1A3/ST1A4 antibody, ST1A5 antibody, STM antibody, TL-PST antibody, thrombomodulin antibody, sulfotransferase family 1A member 3 antibody, THBD antibody, Thbd antibody, SULT1A3 antibody
    背景
    Synonyms: Thrombomodulin
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