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Thrombomodulin 抗体

This anti-Thrombomodulin antibody is a 小鼠 单克隆 antibody detecting Thrombomodulin in FACS, IHC (fro) 和 FM. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2688974
发货至: 中国

Quick Overview for Thrombomodulin 抗体 (ABIN2688974)

抗原

See all Thrombomodulin (THBD) 抗体
Thrombomodulin (THBD)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Thrombomodulin antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Fluorescence Microscopy (FM)

克隆位点

1A4
  • 品牌

    BD Pharmingen™

    产品特性

    Reacts with a 75 kDa, a single chain, type I membrane glycoprotein referred to as thrombomodulin and fetomodulin. CD141 is expressed on endothelial cells, smooth muscle cells, epithelial cells, synovial lining cells, and keratinocytes. It is also found on megakaryocytes, peripheral blood moncytes, and neutrophils, but not on lymphocytes. Reports indicate that CD 141 plays an important role in Protein C activation and the initiation of the Protein C anticoagulant pathway. Thrombin loses its procagulant function when it binds to CD141, and the CD141/thrombin complex is able to activate Protein C. This product is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood monocytes analyzed by flow cytometry.

    BD Pharmingen™ Purified Mouse Anti-Human CD141 - Purified - Clone 1A4 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Aqueous buffered solution containing ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C.
  • Teasdale, Bird, Bird: "Internalization of the anticoagulant thrombomodulin is constitutive and does not require a signal in the cytoplasmic domain." in: Immunology and cell biology, Vol. 72, Issue 6, pp. 480-8, (1995) (PubMed).

  • 抗原

    Thrombomodulin (THBD)

    别名

    CD141

    背景

    Synonyms: Thrombomodulin
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