IL3RA 抗体 (Biotin)
Quick Overview for IL3RA 抗体 (Biotin) (ABIN2688936)
抗原
See all IL3RA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
品牌
- BD Pharmingen™
-
产品特性
-
Reacts with the 70 kDa IL-3 receptor α chain(IL-3Rα), which associates with the 120-140 kDa β subunit. The β chain is shared with the receptors for interleukins IL-5 and GM-CSF. IL-3Rα is expressed on myeloid precursors, basophils, mast cells, macrophages, and megakaryocytes. Reports indicate that IL-3Rα is also expressed on lymphocytes. IL-3R plays an important role in hematopoietic progenitor cell growth and differentiation. This antibody does not block binding of IL-3 to the IL-3 receptor. Profile of TF-1 (erythroid leukemia) cells analyzed on a FACScan
BD Pharmingen™ Biotin Mouse Anti-Human CD123 - Biotin - Clone 9F5 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.5 mg -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
-
亚型
- IgG1 kappa
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
-
储存条件
- 4 °C
-
储存方法
- Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
-
-
-
: "Characterization of human leucocytes bearing the IL-3 receptor." in: Cellular immunology, Vol. 168, Issue 1, pp. 59-68, (1996) (PubMed).
: "Monoclonal antibody 7G3 recognizes the N-terminal domain of the human interleukin-3 (IL-3) receptor alpha-chain and functions as a specific IL-3 receptor antagonist." in: Blood, Vol. 87, Issue 1, pp. 83-92, (1996) (PubMed).
: "The use of avidin-biotin interaction in immunoenzymatic techniques." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 27, Issue 8, pp. 1131-9, (1979) (PubMed).
-
: "Characterization of human leucocytes bearing the IL-3 receptor." in: Cellular immunology, Vol. 168, Issue 1, pp. 59-68, (1996) (PubMed).
-
- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
-
别名
- CD123
-
背景
- Synonyms: IL-3 Receptor α chain
-
途径
- JAK/STAT Signaling
抗原
-