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IL3RA 抗体 (Biotin)

Cited in 3+ publications. This anti-IL3RA antibody is a 小鼠 单克隆 antibody detecting IL3RA in FACS 和 FM. Suitable for 人.
产品编号 ABIN2688936
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IL3RA 抗体 (Biotin) (ABIN2688936)

抗原

See all IL3RA 抗体
IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL3RA antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS), Fluorescence Microscopy (FM)

克隆位点

9F5
  • 产品特性

    Reacts with the 70 kDa IL-3 receptor α chain(IL-3Rα), which associates with the 120-140 kDa β subunit. The β chain is shared with the receptors for interleukins IL-5 and GM-CSF. IL-3Rα is expressed on myeloid precursors, basophils, mast cells, macrophages, and megakaryocytes. Reports indicate that IL-3Rα is also expressed on lymphocytes. IL-3R plays an important role in hematopoietic progenitor cell growth and differentiation. This antibody does not block binding of IL-3 to the IL-3 receptor. Profile of TF-1 (erythroid leukemia) cells analyzed on a FACScan

    BD Pharmingen™ Biotin Mouse Anti-Human CD123 - Biotin - Clone 9F5 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.5 mg

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Aqueous buffered solution containing ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
  • Macardle, Chen, Shih, Huang, Weedon, Sun, Lopez, Zola: "Characterization of human leucocytes bearing the IL-3 receptor." in: Cellular immunology, Vol. 168, Issue 1, pp. 59-68, (1996) (PubMed).

    Sun, Woodcock, Rapoport, Stomski, Korpelainen, Bagley, Goodall, Smith, Gamble, Vadas, Lopez: "Monoclonal antibody 7G3 recognizes the N-terminal domain of the human interleukin-3 (IL-3) receptor alpha-chain and functions as a specific IL-3 receptor antagonist." in: Blood, Vol. 87, Issue 1, pp. 83-92, (1996) (PubMed).

    Guesdon, Ternynck, Avrameas: "The use of avidin-biotin interaction in immunoenzymatic techniques." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 27, Issue 8, pp. 1131-9, (1979) (PubMed).

  • 抗原

    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

    别名

    CD123

    背景

    Synonyms: IL-3 Receptor α chain

    途径

    JAK/STAT Signaling
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