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IL3RA 抗体

This anti-IL3RA antibody is a 小鼠 单克隆 antibody detecting IL3RA in FACS, WB 和 IF. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN2688933
发货至: 中国

Quick Overview for IL3RA 抗体 (ABIN2688933)

抗原

See all IL3RA 抗体
IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL3RA antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF)

克隆位点

9F5
  • 品牌

    BD Pharmingen™

    产品特性

    Reacts with the 70 kDa IL-3 receptor α chain(IL-3Rα), which associates with the 120-140 kDa β subunit. The β chain is shared with the receptors for interleukins IL-5 and GM-CSF. IL-3Rα is expressed on myeloid precursors, basophils, mast cells, macrophages, and megakaryocytes. Reports indicate that IL-3Rα is also expressed on lymphocytes. IL-3R plays an important role in hematopoietic progenitor cell growth and differentiation. This antibody does not block binding of IL-3 to the IL-3 receptor. Log Fluorescence Intensity Profile of TF-1(erythroid leukemia) cells analyzed on a FACScan (

    BD Pharmingen™ Purified Mouse Anti-Human CD123 - Purified - Clone 9F5 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.5 mg

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Aqueous buffered solution containing ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C.
  • Macardle, Chen, Shih, Huang, Weedon, Sun, Lopez, Zola: "Characterization of human leucocytes bearing the IL-3 receptor." in: Cellular immunology, Vol. 168, Issue 1, pp. 59-68, (1996) (PubMed).

    Sun, Woodcock, Rapoport, Stomski, Korpelainen, Bagley, Goodall, Smith, Gamble, Vadas, Lopez: "Monoclonal antibody 7G3 recognizes the N-terminal domain of the human interleukin-3 (IL-3) receptor alpha-chain and functions as a specific IL-3 receptor antagonist." in: Blood, Vol. 87, Issue 1, pp. 83-92, (1996) (PubMed).

  • 抗原

    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

    别名

    CD123

    背景

    Synonyms: IL-3 Receptor α chain

    途径

    JAK/STAT Signaling
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