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Integrin beta 4 抗体

This anti-Integrin beta 4 antibody is a 小鼠 单克隆 antibody detecting Integrin beta 4 in WB, IP, FM 和 ICS. Suitable for 人. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN2688877
发货至: 中国

Quick Overview for Integrin beta 4 抗体 (ABIN2688877)

抗原

See all Integrin beta 4 (ITGB4) 抗体
Integrin beta 4 (ITGB4)

适用

  • 92
  • 27
  • 24
  • 4
  • 4

宿主

  • 65
  • 38
  • 10
  • 2
小鼠

克隆类型

  • 58
  • 57
单克隆

标记

  • 65
  • 9
  • 7
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Integrin beta 4 antibody is un-conjugated

应用范围

  • 59
  • 50
  • 43
  • 34
  • 23
  • 22
  • 16
  • 13
  • 13
  • 13
  • 9
  • 8
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP), Fluorescence Microscopy (FM), Intracellular Staining (ICS)

克隆位点

450
  • 品牌

    BD Pharmingen™

    产品特性

    Reacts with CD104, integrin β4 chain, a 205 kDa transmembrane glycoprotein, associated with CD49f (integrin α6 chain) to form the α6/β4 (CD49f/CD104) complex. CD104 is expressed on epithelial cells, Schwann cells, and some tumor cells. The CD49f/CD104 complex is located in the hemidesmosomes of the epidermis, suggesting its role in epidermal cell-basement membrane adhesion. The clone 450-11A recognizes the cytoplasmic domain of human CD104. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of intracellular A431 cells, an epidermal carcinoma cell line, analyzed by flow cytometry

    BD Pharmingen™ Purified Mouse Anti-Human CD104 - Purified - Clone 450-11A - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Aqueous buffered solution containing ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C.
  • Jones, Kurpakus, Cooper, Quaranta: "A function for the integrin alpha 6 beta 4 in the hemidesmosome." in: Cell regulation, Vol. 2, Issue 6, pp. 427-38, (1991) (PubMed).

    Sonnenberg, Calafat, Janssen, Daams, van der Raaij-Helmer, Falcioni, Kennel, Aplin, Baker, Loizidou: "Integrin alpha 6/beta 4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesion." in: The Journal of cell biology, Vol. 113, Issue 4, pp. 907-17, (1991) (PubMed).

    Kennel, Epler, Lankford, Foote, Dickas, Canamucio, Cavalierie, Cosimelli, Venturo, Falcioni: "Second generation monoclonal antibodies to the human integrin alpha 6 beta 4." in: Hybridoma, Vol. 9, Issue 3, pp. 243-55, (1990) (PubMed).

    Tamura, Rozzo, Starr, Chambers, Reichardt, Cooper, Quaranta: "Epithelial integrin alpha 6 beta 4: complete primary structure of alpha 6 and variant forms of beta 4." in: The Journal of cell biology, Vol. 111, Issue 4, pp. 1593-604, (1990) (PubMed).

    Hemler, Crouse, Sonnenberg: "Association of the VLA alpha 6 subunit with a novel protein. A possible alternative to the common VLA beta 1 subunit on certain cell lines." in: The Journal of biological chemistry, Vol. 264, Issue 11, pp. 6529-35, (1989) (PubMed).

  • 抗原

    Integrin beta 4 (ITGB4)

    别名

    CD104

    背景

    Synonyms: Integrin β4 chain

    途径

    Integrin Complex
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