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Integrin beta 4 抗体

This anti-Integrin beta 4 antibody is a 小鼠 单克隆 antibody detecting Integrin beta 4 in FACS 和 IHC (fro). Suitable for 人. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN2688876
发货至: 中国

Quick Overview for Integrin beta 4 抗体 (ABIN2688876)

抗原

See all Integrin beta 4 (ITGB4) 抗体
Integrin beta 4 (ITGB4)

适用

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  • 4
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宿主

  • 65
  • 38
  • 10
  • 2
小鼠

克隆类型

  • 58
  • 57
单克隆

标记

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This Integrin beta 4 antibody is un-conjugated

应用范围

  • 59
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Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

450
  • 品牌

    BD Pharmingen™

    产品特性

    Reacts with CD104, integrin β4 chain, a 205 kDa transmembrane glycoprotein which associates with CD49f (integrin α6 chain) to form the α6/β4 (CD49f/CD104) complex. CD104 is expressed on epithelial cells, Schwann cells, and some tumor cells. The CD49f/CD104 complex is located in the hemidesmosomes of the epidermis, suggesting its role in epidermal cell-basement membrane adhesion. The clone 450-9D recognizes the extracellular domain of human CD104 and is able to block the binding of clone 439-9B (another CD104 clone) to A431 cells. 450-9D is effective in flow cytometry and immunohistochemistry on frozen sections. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of A431, an epidermal carcinoma cell line, analyzed by flow cytometry

    BD Pharmingen™ Purified Mouse Anti-Human CD104 - Purified - Clone 450-9D - Isotype Mouse IgG1, λ - Reactivity Hu - 0.1 mg

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    亚型

    IgG1 lambda
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Aqueous buffered solution containing ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C.
  • Jones, Kurpakus, Cooper, Quaranta: "A function for the integrin alpha 6 beta 4 in the hemidesmosome." in: Cell regulation, Vol. 2, Issue 6, pp. 427-38, (1991) (PubMed).

    Sonnenberg, Calafat, Janssen, Daams, van der Raaij-Helmer, Falcioni, Kennel, Aplin, Baker, Loizidou: "Integrin alpha 6/beta 4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesion." in: The Journal of cell biology, Vol. 113, Issue 4, pp. 907-17, (1991) (PubMed).

    Kennel, Epler, Lankford, Foote, Dickas, Canamucio, Cavalierie, Cosimelli, Venturo, Falcioni: "Second generation monoclonal antibodies to the human integrin alpha 6 beta 4." in: Hybridoma, Vol. 9, Issue 3, pp. 243-55, (1990) (PubMed).

    Hemler, Crouse, Sonnenberg: "Association of the VLA alpha 6 subunit with a novel protein. A possible alternative to the common VLA beta 1 subunit on certain cell lines." in: The Journal of biological chemistry, Vol. 264, Issue 11, pp. 6529-35, (1989) (PubMed).

  • 抗原

    Integrin beta 4 (ITGB4)

    别名

    CD104

    背景

    Synonyms: Integrin β4 chain

    途径

    Integrin Complex
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